Overview

Yersinia strains are important human pathogens causing diseases ranging from the deadly Plague (Yersinia pestis) to a relatively mild gastroenteritis (e.g. Y. enterocolitica and Y. pseudotuberculosis). Plague is currently classed as a re-emerging disease that is endemic in many parts of the world. Since Y. pestis is highly lethal (a very small number of bacilli are enough to kill someone in a matter of days) it could be used by bioterrorists as a formidable airborne adversary. This has provided the impetus for a renewed interest in Yersinia molecular and cellular biology. Written by the top Yersinia specialists, the book reviews the molecular biology of these important organisms and comprehensively covers recent advances in the field. Topics include genetic diversity in Y. pestis, quorum sensing, identification of virulence genes, regulation of virulence elements, superantigens, host invasion, host immune response, LPS structure and genetics, flagellar-dependent motility, flagellar-dependent protein secretion, iron or heme transport systems, Yersinia pathogenicity Islands, the Yop effector proteins, plasminogen activator (Pla), F1 antigen, and the conjugative plasmid pVM82. Essential reading for everyone with an interest in Yersinia and recommended reading for other scientists with an interest in, for example, bioterrorism, microbial pathogenesis, microbial genomics, and antimicrobials.

Full Product Details

Author:   Elisabeth Carniel (Institut Pasteur, France) ,  B. Joseph Hinnesbusch (National Institute of Allgery and Infectious Diseases, USA)
Publisher:   Taylor & Francis Ltd
Imprint:   Horizon
Dimensions:   Width: 17.80cm , Height: 2.50cm , Length: 25.40cm
Weight:   0.975kg
ISBN:  

9781904933069

ISBN 10:   1904933068
Pages:   452
Publication Date:   02 December 2004
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   No Longer Our Product
Availability:   In Print  
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Reviews

It is accurate, thorough and for a book of this type, up-to-date. A credit to all contributors. This book is a must for Yersiniologists, but may also have wider appeal for researchers interested in biodefence, microbial genomics and the evolution of microbial virulence. - Brendan Wren, London School of Hygiene & Tropical Medicine It is a contributive and solid foundation on which to base continuous bibliographic updating in a bacterial field evolving at least as fast as the Yersinia speicies themselves - Clinical Infectious Diseases, 2004:41, 15 December

Author Information

Elisabeth Carniel

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