Overview

An indispensable guide to an emerging technology, this unique book introduces detailed methods for the construction, screening, and use of DNA sequences cloned into yeast artificial chromosome (YAC) vectors and the applications of YACs to gene hunting. Also covered are the reconstruction of large genes and the analysis of YACs by insertion back into mammalian cells--a method that may lead to the therapeutic use of YAC clones. The methods described are drawn from work on human DNA, but are universal to yeast artificial chromosomes used in other organisms. YAC Libraries is the third volume in the UWBC Biotechnical Resource Series with Dr. Richard Burgess, Director of the University of Wisconsin Biotechnology center, as Series Editor. The series is dedicated to providing practical guidance to researchers exploring new technologies and services.

Full Product Details

Author:   David L. Nelson ,  Bernard Brownstein
Publisher:   Macmillan Learning
Imprint:   W.H.Freeman & Co Ltd
Dimensions:   Width: 15.00cm , Height: 1.40cm , Length: 23.00cm
Weight:   0.310kg
ISBN:  

9780716770145

ISBN 10:   0716770148
Pages:   240
Publication Date:   23 September 1993
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Temporarily unavailable  
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Cover[s] a wide range of topics and methodologies. --Journal of Chemical Education<br>

Cover[s] a wide range of topics and methodologies. --Journal of Chemical Education Cover[s] a wide range of topics and methodologies. --Journal of Chemical Education Cover[s] a wide range of topics and methodologies. --Journal of Chemical Education Cover[s] a wide range of topics and methodologies. --Journal of Chemical Education Cover�s� a wide range of topics and methodologies. --Journal of Chemical Education

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