Overview

This study describes how proteins encoded by the larger DNA viruses (such as poxviruses, herpesviruses and adenoviruses) interact with elements of the vertebrate immune system to favour propagation in infected hosts. All mammalian viruses in the wild have adapted to the selection pressure exerted by the various effector arms of the immune apparatus, but the DNA viruses with larger genomes have the luxury of being able to encode and express specific viral proteins whose function is to directly subvert or modulate immune recognition and clearance. Up-to-date information is provided of how such viral immune regulator proteins have co-evolved with the host proteins that mediate natural and acquired immunity.

Full Product Details

Author:   Grant McFadden
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Weight:   0.815kg
ISBN:  

9783540589013

ISBN 10:   3540589015
Pages:   232
Publication Date:   20 January 1995
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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