Free Delivery Over $100
|
|
|||
|
||||
OverviewFor a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism. The multi-faceted interplay between viral and cellular factors during virus entry is a fascinating field of study, which can provide important insight into viral pathogenesis and define new targets for intervention. This book provides a comprehensive overview of this exciting field of research. Full Product DetailsAuthor: Stefan Pöhlmann , Graham SimmonsPublisher: Springer-Verlag New York Inc. Imprint: Springer-Verlag New York Inc. Edition: 2013 ed. Volume: 790 Dimensions: Width: 15.50cm , Height: 1.80cm , Length: 23.50cm Weight: 0.488kg ISBN: 9781461476504ISBN 10: 146147650 Pages: 199 Publication Date: 17 June 2013 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationSTEFA N PÖHLMANN is Professor for Infection Biology and Head of the Infection Biology Unit of the German Primate Center. His research is focused on virus host cell interactions, particularly on the molecular processes underlying host cell entry of human immunodeficiency virus and emerging viruses. Stefan Pöhlmann received his academic degrees (Dr. rer. nat., venia legendi) from the Friedrich‑Alexander‑University Erlangen‑Nurnberg. Before his appointment at the German Primate Center, he worked as a postdoctoral fellow at the University of Pennsylvania, as a junior research group leader at the Friedrich‑Alexander‑University Erlangen‑Nurnberg and as an assistant professor at Hannover Medical School. He serves on the editorial board of the Journal of Virology and Virology and serves as academic editor for PLoS ONE. GRAHAM SIMMONS is an Associate Investigator at Blood Systems Research Institute and Associate Professor in the Department of Laboratory Medicine at the University of California, San Francisco. He is interested in many aspects of viral entry, particularly for blood transfusion transmissible agents and other emerging and re‑emerging viruses that may be a threat to the blood supply. Graham Simmons received his doctoral training from the Institute of Cancer Research in London prior to performing an EMBO‑sponsored postdoctoral fellowship at the University of Pennsylvania. Tab Content 6Author Website:Countries AvailableAll regions |
||||
