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OverviewTreatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. The assessment and management of refractory patients with mood disorders is a major clinical challenge for mental health providers. Part of the Oxford Psychiatry Library (OPL) series, this pocketbook provides a concise view of the current definitions, assessment and evidence-based management of treatment-resistant mood disorders and reviews novel therapeutic targets for mood disorders, which may enhance the therapeutic armamentarium of clinicians in the near future. The pocketbook serves as a useful guide for mental health practitioners, including psychiatrists, clinical psychologists, trainees, and interested primary care physicians. Full Product DetailsAuthor: André F Carvalho (Associate Professor of Psychiatry, Associate Professor of Psychiatry, Psychiatry Research Group Faculty of Medicine, Federal University of Ceará, Fortaleza, CE Brazil) , Roger S McIntyre (Professor of Psychiatry and Pharmacology, Professor of Psychiatry and Pharmacology, Mood Disorders Psychopharmacology Unit, University of Toronto)Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 13.00cm , Height: 1.00cm , Length: 19.30cm Weight: 0.197kg ISBN: 9780198707998ISBN 10: 0198707991 Pages: 176 Publication Date: 26 March 2015 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1: Marcelo T. Berlim, Santiago Tovar-Perdomo and Marcelo P. A. Fleck: Treatment-resistant major depressive disorder: Current Definitions, Epidemiology and Assessment 2: Chris Abbott and Mauricio Tohen: Treatment-resistant bipolar disorder: current definitions, epidemiology and assessment 3: Jelena Vrublevska and Konstantinos N. Fountoulakis: Determinants of Treatment Resistance: Health Systems and Public Policy Implications 4: Sheng-Min Wang and Chi-Un Pae: The influence of psychiatric and medical comorbidities in treatment resistance for mood disorders 5: Andrew Haddon Kemp, André Russowsky Brunoni and Rodrigo Machado-Vieira: Predictors of treatment response in major depressive disorder 6: Benicio N. Frey: Predictors of Treatment Response in Bipolar Disorder: Lessons from Longitudinal Studies 7: André F. Carvalho, Thomas N. Hyphantis and Roger S. McIntyre: Evidence-based Pharmacological Approaches for Treatment-Resistant Major Depressive Disorder 8: Poon SH and Sim K: Evidence-based pharmacological approaches for treatment-resistant bipolar disorder 9: Jenny Guidi and Giovanni A. Fava: Psychosocial management of treatment-resistant mood disorders: current evidence 10: Eric Cretaz, Alexandre Duarte Gigante and Beny Lafer: Electroconvulsive therapy for treatment-resistant mood disorders 11: André Russowsky Brunoni, Pedro Shiozawa and Felipe Fregni: Novel non-invasive brain stimulation approaches for treatment-resistant mood disorders 12: Giacobbe P, Lipsman N, Lozano A and Kennedy SH: Vagus Nerve Stimulation and Deep Brain Stimulation: Implantable Device-Related Neurostimulation for Treatment-Resistant Mood Disorders 13: Marcio Gerhardt Soeiro-de-Souza and Rodrigo Machado-Vieira: Novel Therapeutic Targets for Major Depressive Disorder 14: Seetal Dodd: Novel therapeutic targets for bipolar disorderReviewsAlthough small, this book provides a wealth of information about an extremely important area that is frequently misunderstood and undertreated. It is a useful read for all psychiatrists, but is a must read for all psychiatric residents. * Michael Easton, MD (Rush University Medical Center); Doodys Reviews * "`This is an excellent topic for such a book, and one that has been well conceptualized. The combination of MDD and BPD in one resource is in keeping with the clinical realities, including the uncertainty of diagnosis or the need to reconsider the diagnosis when treatment resistance occurs.' Larry Culpepper, MD, MPH, Chair, Department of Family Medicine, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, USA `There is a real need for this in multiple domains. First as a resource for clinicians both regarding to practical issues but also in providing an expertly informed conceptual framework for thinking about TRD and about strategies for escalating therapy in those potentially treatment resistant.' Larry Culpepper, MD, MPH, Chair, Department of Family Medicine, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, USA `Innovative approaches such as ""Determinants of treatment resistance: Health systems and public policy implications""; ""Novel non-invasive brain stimulation approaches for treatment-resistant mood disorders""; ""Novel therapeutic targets for major depressive disorder"" ... will be well received.' Sergio A. Strejilevich, Bipolar Disorder Program, Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina" This is an excellent topic for such a book, and one that has been well conceptualized. The combination of MDD and BPD in one resource is in keeping with the clinical realities, including the uncertainty of diagnosis or the need to reconsider the diagnosis when treatment resistance occurs. Larry Culpepper, MD, MPH, Chair, Department of Family Medicine, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, USA This will be a unique resource that combines MDD and BPD, and is up to date and evidence based. Larry Culpepper, MD, MPH, Chair, Department of Family Medicine, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, USA There is a real need for this in multiple domains. First as a resource for clinicians both regarding to practical issues but also in providing an expertly informed conceptual framework for thinking about TRD and about strategies for escalating therapy in those potentially treatment resistant. Larry Culpepper, MD, MPH, Chair, Department of Family Medicine, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, USA Innovative approaches such as Determinants of treatment resistance: Health systems and public policy implications ; Novel non-invasive brain stimulation approaches for treatment-resistant mood disorders ; Novel therapeutic targets for major depressive disorder ... will be well received. Sergio A. Strejilevich, Bipolar Disorder Program, Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina Although small, this book provides a wealth of information about an extremely important area that is frequently misunderstood and undertreated. It is a useful read for all psychiatrists, but is a must read for all psychiatric residents. Michael Easton, MD (Rush University Medical Center); Doodys Reviews Author Information"Professor André F. Carvalho, MD, PhD, Associate Professor of Psychiatry, Psychiatry Research Group, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE Brazil. ; Roger S. McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto and Head of the Mood Disorders Psychopharmacology Unit at the University Health Network, Toronto, Canada. He was named by Thomson Reuters in 2014 as one of ""The World's Most Influential Scientific Minds"" for publishing the largest number of articles that rank among those most frequently cited by researchers globally during the previous decade. Dr. McIntyre is involved in multiple research endeavours which primarily aim to characterize the association between mood disorders, notably cognitive function and medical comorbidity. This body of work has provided a platform for identifying novel molecular targets to treat and prevent mood disorders and accompanying cognitive impairment." 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