Overview

This title provides investigators and graduate students with overviews of developments in the field of protein biosynthesis that are fuelled by the explosive and synergic growth of structural biology, genomics, and bioinformatics. The outstanding progress in our understanding of the structure, dynamics, and evolution of the prokaryotic and eukaryotic translation machinery, as well as applications in medicine and biotechnology, are described in 26 chapters covering discoveries on: the subtleties of tRNA aminoacylation with natural and unnatural amino acids; the control of mRNA stability, a key step of gene regulation; ribosome structure and function, in the era of the atomic-crystal resolution of the ribosome; the regulation of the biosynthesis of the translational machinery components; the action of a variety of inhibitors of translation and the prospect for clinical studies.

Full Product Details

Author:   Jacques Lapointe ,  Lea Brakier-Gigras
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   2003 ed.
Dimensions:   Width: 15.50cm , Height: 3.10cm , Length: 23.50cm
Weight:   0.913kg
ISBN:  

9780306478390

ISBN 10:   0306478390
Pages:   468
Publication Date:   31 July 2003
Audience:   General/trade ,  Professional and scholarly ,  General ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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