Free Delivery Over $100
|
|
|||
|
||||
OverviewG protein-coupled receptors (GPCRs) constitute the largest superfamily of cell surface receptors that regulate a variety of cell functions. Over the past few decades great progress has been made in defining the roles of intracellular trafficking in controlling the functionality of the receptors as well as in the development of various human diseases. This volume of Progress in Molecular Biology and Translational Science reviews the recent understanding of GPCR trafficking regulators and molecular mechanisms. Full Product DetailsAuthor: Guangyu Wu (Georgia Regents University)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Volume: 132 Dimensions: Width: 15.20cm , Height: 2.40cm , Length: 22.90cm Weight: 0.660kg ISBN: 9780128029398ISBN 10: 0128029390 Pages: 328 Publication Date: 02 June 2015 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsArrestins: Critical Players in Trafficking of Many GPCRs Vsevolod V. Gurevich and Eugenia V. Gurevich Regulation of GPCR Trafficking by Ubiquitin Justine E. Kennedy and Adriano Marchese Rhodopsin Trafficking and Mistrafficking: Signals, Molecular Components and Mechanisms Ina Nemet, Philip Ropelewski and Yoshikazu Imanishi Intracellular Trafficking of Neuropeptide Y Receptors Karin Mörl and Annette G. Beck-Sickinger Insights into Serotonin Receptor Trafficking: Cell Membrane Targeting and Internalization Michèle Darmon, Sana Al Awabdh , Michel-Boris Emerit and Justine Masson Calcium-Sensing Receptor: Trafficking, Endocytosis, Recycling and Importance of Interacting Proteins Kausik Ray Trafficking of ß Adrenergic Receptors: Implications in Intracellular Receptor Signaling Qin Fu and Yang K. Xiang Post-endocytic sorting of Adrenergic and Opioid Receptors: New Mechanisms and Functions. Shanna L. Bowman and Manojkumar A. Puthenveedu a2 Adrenergic Receptor Trafficking as a Therapeutic Target in Antidepressant Drug Action Christopher Cottingham, Craig J. Ferryman and Qin Wang Regulation of a2B-Adrenerigc Receptor Export Trafficking by Specific Motifs Guangyu Wu, Jason E. Davis and Maoxiang Zhang Temperature-Sensitive Intracellular Traffic of ?2c-Adrenergic Receptor Catalin M. Filipeanu N-Terminal Signal Peptides of G Protein-Coupled Receptors: Significance for Receptor Biosynthesis, Trafficking and Signal Transduction Claudia Rutz, Wolfgang Klein and Ralf Schülein Regulation of GPCR Anterograde Trafficking by Molecular Chaperones and Motifs Brent Young, Jaime Wertman and Denis J. DupréReviewsAuthor InformationDr. Guangyu Wu, the editor of this book, is a professor in the Department of Pharmacology and Toxicology at the Medical College of Georgia, Georgia Regents University. The long term goal of Dr. Wu’s research effort is to define the molecular mechanisms underlying the intracellular trafficking and signal propagation of GPCRs. Dr. Wu’s research at the earlier stages, as a graduate student and a post-doctoral fellow, was mainly on the GPCR pharmacology and signal transduction pathways. Since starting his own laboratory in the Department of Pharmacology at Louisiana State University Health Sciences Center New Orleans, Dr. Wu has focused his research on the regulation of GPCR export from the endoplasmic reticulum through the Golgi apparatus to the cell surface through studying the function of well-defined transport machinery at different intracellular organelles and defining specific motifs embedded within the receptors that direct receptor export from the ER/Golgi or cell surface transport. Tab Content 6Author Website:Countries AvailableAll regions |
||||
