Overview

Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans. The chapters focus on occupational safety and consumer issues and examine the circumstances under which exposure is likely to occur. To be in context, it reviews this against the background of adverse health effects from other sources in the veterinary and farming professions. The book examines adverse drug effects reported to regulatory agencies (mainly the FDAAEs Center for Veterinary Medicine) and then considers a series of individual drugs, including antibiotics, anaesthetics and organophosphorus compounds. The chapters also discuss the fundamental aspects of regulatory issues relating to safety assessment, and examine the manner in which user safety is assessed prior to authorisation/approval and what measures can be taken after authorisation/approval in the light of findings from pharmacovigilance activities. There is growing concern over the issue of antimicrobial resistance and the contribution made by veterinary medicinal products. This too is addressed along with the significance to human health and measures that can be taken to mitigate the effects (if any) of the use of antibiotics in animals e.g. prudent use measures. The book is an essential resource for medical practitioners in hospitals and general practice, pharmaceutical industry scientists, analysts, regulators and risk managers.

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9781849736855

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Since 1984 Dr. Kevin Woodward's experience has been centred on all aspects of the evaluation and regulation of veterinary drugs, particularly from the point of view of safety evaluation, toxicology, user risk assessment and pharmacovigilance. He was a member of the Committee for Veterinary Medicinal Products (CVMP) until August 1996 and Chairman of its Safety of Residues Working Group from 1991 until 1996. He was a member of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and an invited expert to the Committee for the years 1988-1996. He has also been leader of the UK delegation to the Codex Committee on Residues of Veterinary Drugs in Food from 1993 to 1996. From September 1997 until September 1999, and again from 1999 until November 2001, he chaired IFAH-Europe's (formerly FEDESA's) Technical and Regulatory Committee and was elected to the Board of Directors of FEDESA in February 2002 and to the Board of Directors of NOAH (ex-officio), also in February 2002. Since 2008, he has been the Regulatory Officer for the EAVPT.

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