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Author:   Pritam S. Sahota ,  James A. Popp (Stratoxon LLC, Lancaster, Pennsylvania, USA) ,  Jerry F. Hardisty (Experimental Pathology Laboraties, Inc., Research Triangle Park, North Carolina, USA) ,  Chirukandath Gopinath (Independent Consultant, Huntingdon, UK)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Edition:   2nd edition
Weight:   1.732kg
ISBN:  

9781498745307

ISBN 10:   149874530
Pages:   1244
Publication Date:   27 August 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9781032319193
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Preface Acknowledgments Editors Contributors Section I Concepts in Drug Development Chapter 1 Overview of Drug Development James A. Popp and Jeffery A. Engelhardt Chapter 2 Nonclinical Safety Evaluation of Drugs Thomas M. Monticello and Jeanine L. Bussiere Chapter 3 Nonclinical Safety Evaluation of Advanced Therapies Timothy K. MacLachlan, Kendall S. Frazier, and Mercedes Serabian Chapter 4 Nonclinical Safety Evaluation of Medical Devices Kathleen A. Funk, Victoria A. Hampshire, and JoAnn C. L. Schuh Chapter 5 Pathology and the Pathologist in Pharmaceutical Research and Development Page R. Bouchard, Christopher J. Clarke, and Dominique Brees Chapter 6 Routine and Special Techniques in Toxicologic Pathology Daniel J. Patrick, Matthew L. Renninger, and Peter C. Mann Chapter 7 Principles of Clinical Pathology Niraj K. Tripathi and Jacqueline M. Tarrant Chapter 8 Toxicokinetics and Drug Disposition David D. Christ Chapter 9 Toxicogenomics in Toxicologic Pathology Arun R. Pandiri, David E. Malarkey, and Mark J. Hoenerhoff Chapter 10 Spontaneous Lesions in Control Animals Used in Toxicity Studies Robert C. Johnson, Robert H. Spaet, Gitte Jeppesen, Ursula Junker, and Robert Stull Section II Organ Systems Chapter 11 Gastrointestinal Tract Judit E. Markovits, Graham R. Betton, Donald N. McMartin, and Theresa Boulineau Chapter 12 Liver, Gallbladder, and Exocrine Pancreas Russell C. Cattley, James A. Popp, and Steven L. Vonderfecht Chapter 13 Respiratory System Tom P. McKevitt and David J. Lewis Chapter 14 Urinary System Kendall S. Frazier and John Curtis Seely Chapter 15 Hematopoietic System Kristin Henson, Tanasa Osborne, and Gregory S. Travlos Chapter 16 The Lymphoid System Patrick J. Haley Chapter 17 Bone, Muscle, and Tooth John L. Vahle, Joel R. Leininger, Philip H. Long, D. Greg Hall, and Heinrich Ernst Chapter 18 The Cardiovascular System Calvert Louden, David Brott, Chidozie J. Amuzie, Bindu Bennet, and Ronnie Chamanza Chapter 19 Endocrine Glands Richard A. Peterson, Sundeep Chandra, and Mark J. Hoenerhoff Chapter 20 Reproductive System and Mammary Gland Justin D. Vidal, Charles E. Wood, Karyn Colman, Katharine M. Whitney, and Dianne M. Creasy Chapter 21 Skin Zbigniew W. Wojcinski, Lydia Andrews-Jones, Daher Ibrahim Aibo, Rie Kikkawa, and Robert Dunstan Chapter 22 Nervous System Mark T. Butt, Alys Bradley, and Robert Sills Chapter 23 Special Senses: Eye and Ear Kenneth A. Schafer, Oliver C. Turner, and Richard A. Altschuler Index

Reviews

This book has much to recommend it to both the experienced toxicologist and toxicologic pathologist and to beginners in the field of drug development. The accumulated knowledge of the contributing authors, much of which has never been published before, makes this a classic that should be in use for many years to come. -John R. Foster, ToxPath Sciences Ltd, Congleton, Cheshire, UK Full review available at: https://journals.sagepub.com/doi/pdf/10.1177/0192623319861939

...the editors have achieved a truly remarkable feat in pulling together over 70 of the top toxicologic pathologists, the majority of whom are still practicing in their respective fields. This book has much to recommend it to both the experienced toxicologist and toxicologic pathologist and to beginners in the field of drug development. The accumulated knowledge of the contributing authors, much of which has never been published before, makes this a classic that should be in use for many years to come. -John R. Foster, ToxPath Sciences Ltd, Congleton, Cheshire, UK Toxicologic Pathology 2019, Vol. 47(7) 902 Full review available at: https://journals.sagepub.com/doi/pdf/10.1177/0192623319861939 ...the editors have achieved a truly remarkable feat in pulling together over 70 of the top toxicologic pathologists, the majority of whom are still practicing in their respective fields. This book has much to recommend it to both the experienced toxicologist and toxicologic pathologist and to beginners in the field of drug development. The accumulated knowledge of the contributing authors, much of which has never been published before, makes this a classic that should be in use for many years to come. -John R. Foster, ToxPath Sciences Ltd, Congleton, Cheshire, UK Toxicologic Pathology 2019, Vol. 47(7) 902 Full review available at: https://journals.sagepub.com/doi/pdf/10.1177/0192623319861939

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