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OverviewThe potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools are explored in this volume, which is the proceedings of the 7th NIH Symposium on Therapeutic Oligonucleotides. The focus is on antisense, RNAi, triple-helix, gene repair, DNA chips, and CpG immune modulatory oligonucleotides. Specific chapters address designing better siRNAs, splice switching oligonucleotides, selective delivery of oligonucleotides, and medicinal drugs by receptor-mediated endocytosis, development of a function overriding siRNA silencing in mammalian cells, transcription factor decoys, and modified oligonucleotide hybridization and genetic insertion. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. Full Product DetailsAuthor: Yoon S. Cho-Chung (National Cancer Institute, National Institutes of Health, Bethesda, MD, USA) , Alan M. Gewirtz (University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania) , Cy A. Stein (Albert Einstein College of Medicine, New York, USA)Publisher: John Wiley and Sons Ltd Imprint: Wiley-Blackwell Dimensions: Width: 15.50cm , Height: 1.50cm , Length: 22.90cm Weight: 0.399kg ISBN: 9781573316095ISBN 10: 1573316091 Pages: 284 Publication Date: 26 July 2006 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Out of stock The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsReviewsAuthor InformationYoon S. Cho-Chung and Alan M. Gewirtz are the authors of Therapeutic Oligonucleotides: Transcriptional and Translational Strategies for Silencing Gene Expression, Volume 1058, published by Wiley. Tab Content 6Author Website:Countries AvailableAll regions |