Overview

This text examines the applications of Monte Carlo calculations in therapeutic nuclear medicine. This includes basic principles to computer implementations of software packages and their applications in radiation dosimetry and treatment planning. It is written for nuclear medicine physicists and physicians as well as radiation oncologists and can serve as a supplementary text for medical imaging, radiation dosimetry and nuclear engineering graduate courses in science, medical and engineering faculties. With chapters written by recognized authorities in that particular field, the book covers the entire range of MC applications in therapeutic medical and health physics, from its use in imaging prior to therapy to dose distribution modelling in targeted radiotherapy. The contributions discuss the fundamental concepts of radiation dosimetry, radiobiological aspects of targeted radionuclide therapy and the various components and steps required for implementing a dose calculation and treatment planning methodology in radioimmunotherapy. Some computer programmes are described and illustrated with some useful features and clinical applications. Other potential applications of MC techniques are also discussed together with computing aspects of radiation transport calculations.

Full Product Details

Author:   H. Zaidi ,  G Sgouros
Publisher:   Taylor & Francis Ltd
Imprint:   Institute of Physics Publishing
Dimensions:   Width: 15.60cm , Height: 2.50cm , Length: 23.50cm
Weight:   0.794kg
ISBN:  

9780750308168

ISBN 10:   0750308168
Pages:   384
Publication Date:   01 September 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

The Monte Carlo method: theory and computational issues Monte Carlo techniques in nuclear medicine dosimetry Medical imaging techniques for radiation dosimetry Computational methods in internal radiation dosimetry Mathematical models of the human anatomy Monte Carlo codes for use in therapeutic nuclear medicine Dose point kernels for radionuclide dosimetry Radiobiology aspects and radionuclide selection criteria in cancer therapy Microdosimetry of targeted radionuclides The MABDOS program for internal radionuclide dosimetry The 3D-ID three-dimensional internal dosimetry software package Validation and verification of absorbed dose calculations in radionuclide therapy Monte Carlo methods and mathematical models for the dosimetry of skeleton and bone marrow Monte Carlo modeling of dose distributions in intravascular radiation therapy The Monte Carlo method as a design tool in Boron Neutron Capture Synovectomy Summary

Reviews

"The book is generally well written, clearly presented, and very well documented. Each chapter gives an overview of each subject, and it is up to the reader to investigate it further using the extensive bibliography provided. Each topic is discussed from a practical point of view, which is of great help for non-experienced readers. For instance, the chapter about mathematical aspects of Monte Carlo particle transport is very clear and helps one to apprehend the philosophy of the method, which is often a difficulty with a more theoretical approach. This book is very interesting, of practical interest, and it should have its utility in all modern nuclear medicine departments interested in dosimetry, providing up-to-date data and references. It should be viewed as a good and well-documented handbook, or as a general introduction for beginners and students. -- J Coulot, Phys. Med. Biol. 48 (7 August 2003) 2 ""The 2 initial chapters, describing general MC methods and their application to nuclear medical dose estimation, are important. Chapter 6 is useful for its review of various MC computer codes available and the limitations of each. Kassis' description of radiobiology and choice of radionuclide is excellent and contains interesting novel information on cellular bystander effects. Also included is an extended discussion of imaging methods, with emphasis on SPECT and PET. The analysis done at Lund University (Ljungberg and Strand) is particularly interesting for the determination of scatter and attenuation effects in 131I photon detection ...This is a timely review of an important subject. The contributors are of international stature and the editor is congratulated on bringing together thisexpertise."" -- Professor Steve Webb, J Nucl Med 2003 44: pp 991 ""The book is comprehensive and to some extent the title belies the range of content within, as it will appeal to the more general reader as well as to those with a penchant for number-crunching. The introductory material on Monte Carlo modelling is very useful and well written, as are the chapters on imaging for dosimetry and an introduction to radiobiology. This, then, is a very timely book and should be welcomed by the nuclear medicine community. This is, in all, an excellent book and should be compulsory This is, in all, an excellent book and should be compulsory reading for physicians and physicists with an interest in targeted therapy and quantitative imaging. It is likely that the next few years will see a surge in quantitative imaging due to the increasing prevalence of PET, the use of functional imaging for the planning of external beam radiotherapy and the continuing need and legislation for dosimetry for targeted therapies. Certainly for those departments with any interest in targeted therapy, this book is essential."" -- Eur J Nucl Med Mol Imaging (2003) 30: pp 772 ""This book consists of 15 cahpters over 364 pages related to the use of Monte Carlo methodology in nuclear medicine. Starting with an introduction to Monte Carolo, a range of topics are covered that to a greater or lesser extent are linked to the subject. The book is comprehensive and to some extent the title belies the range of content within, as it will appeal to the more general reader as well as to those with a prenchant for number-crunching. The introductory material on Monte Carlo modelling is very useful and well written, as are the chapters onimaging for dosimetry and an introduction to radiobiology ... the book therefore serves both as a useful reference guide and as an introduction to the subjects ... This is, in all, an excellent book and should be compulsory reading for physicians and physicists with an interest in targeted therapy and quantitative imaging ... Certainly, for those departments with any interest in targeted therapy, this book is esential."" -- Glenn Flux, European Journal of Nuclear Medicine and Molecular Imaging"

The book is generally well written, clearly presented, and very well documented. Each chapter gives an overview of each subject, and it is up to the reader to investigate it further using the extensive bibliography provided. Each topic is discussed from a practical point of view, which is of great help for non-experienced readers. For instance, the chapter about mathematical aspects of Monte Carlo particle transport is very clear and helps one to apprehend the philosophy of the method, which is often a difficulty with a more theoretical approach. This book is very interesting, of practical interest, and it should have its utility in all modern nuclear medicine departments interested in dosimetry, providing up-to-date data and references. It should be viewed as a good and well-documented handbook, or as a general introduction for beginners and students. -- J Coulot, Phys. Med. Biol. 48 (7 August 2003) 2 The 2 initial chapters, describing general MC methods and their application to nuclear medical dose estimation, are important. Chapter 6 is useful for its review of various MC computer codes available and the limitations of each. Kassis' description of radiobiology and choice of radionuclide is excellent and contains interesting novel information on cellular bystander effects. Also included is an extended discussion of imaging methods, with emphasis on SPECT and PET. The analysis done at Lund University (Ljungberg and Strand) is particularly interesting for the determination of scatter and attenuation effects in 131I photon detection ...This is a timely review of an important subject. The contributors are of international stature and the editor is congratulated on bringing together thisexpertise. -- Professor Steve Webb, J Nucl Med 2003 44: pp 991 The book is comprehensive and to some extent the title belies the range of content within, as it will appeal to the more general reader as well as to those with a penchant for number-crunching. The introductory material on Monte Carlo modelling is very useful and well written, as are the chapters on imaging for dosimetry and an introduction to radiobiology. This, then, is a very timely book and should be welcomed by the nuclear medicine community. This is, in all, an excellent book and should be compulsory This is, in all, an excellent book and should be compulsory reading for physicians and physicists with an interest in targeted therapy and quantitative imaging. It is likely that the next few years will see a surge in quantitative imaging due to the increasing prevalence of PET, the use of functional imaging for the planning of external beam radiotherapy and the continuing need and legislation for dosimetry for targeted therapies. Certainly for those departments with any interest in targeted therapy, this book is essential. -- Eur J Nucl Med Mol Imaging (2003) 30: pp 772 This book consists of 15 cahpters over 364 pages related to the use of Monte Carlo methodology in nuclear medicine. Starting with an introduction to Monte Carolo, a range of topics are covered that to a greater or lesser extent are linked to the subject. The book is comprehensive and to some extent the title belies the range of content within, as it will appeal to the more general reader as well as to those with a prenchant for number-crunching. The introductory material on Monte Carlo modelling is very useful and well written, as are the chapters onimaging for dosimetry and an introduction to radiobiology ... the book therefore serves both as a useful reference guide and as an introduction to the subjects ... This is, in all, an excellent book and should be compulsory reading for physicians and physicists with an interest in targeted therapy and quantitative imaging ... Certainly, for those departments with any interest in targeted therapy, this book is esential. -- Glenn Flux, European Journal of Nuclear Medicine and Molecular Imaging

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