Overview

The Ionotropic Glutamate Receptors provides the first detailed survey of the biochemical, physiological, and pharmacological properties of recombinant ionotropic glutamate receptors. The distinguished contributors show how the molecular characteristics of these receptors account for many of the properties of native ionotropic glutamate receptors. They also examine in detail the properties of glutamate receptor subunits, including receptor modulation by phosphorylation and the anatomical localization of specific glutamate receptor subunits as determined by in situ hybridization and immunochemistry. The Ionotropic Glutamate Receptors conveys the first clear insights into the molecular bases underlying the wealth of pharmacological and physiological data on these receptors.

Full Product Details

Author:   Daniel Monaghan ,  Robert Wenthold
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1997 ed.
Dimensions:   Width: 15.50cm , Height: 2.50cm , Length: 23.50cm
Weight:   1.640kg
ISBN:  

9780896034563

ISBN 10:   0896034569
Pages:   379
Publication Date:   01 October 1996
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

1 • Subtypes of Glutamate Receptors: Historical Perspectives on Their Pharmacological Differentiation.- 2 • The Topology of Glutamate Receptors: Sorting Through the Domains.- 3 • Ionotropic Glutamate Receptors: Heterogeneity by Posttranscriptional Modifications.- 4 • The Role of Alternative Splicing of the NMDAR1 Receptor Subunit in Synaptic Plasticity.- 5 • Phosphorylation of Non-NMDA Glutamate Receptor Ion Channels: Implications for Synaptic Plasticity and Their Membrane Topology.- 6 • Regulation of NMD A Receptors by Protein Phosphorylation.- 7 • A Map of Non-NMDA Receptor Subunit Expression in the Vertebrate Brain Derived from In Situ Hybridization Histochemistry.- 8 • Developmental Dynamics of Gene Expression for NMDA Receptor Channel.- 9 • Immunocytochemical Localization of Ionotropic Glutamate Receptors (GluRs) in Neural Circuits.- 10 • Functional Properties of Kainate Receptors.- 11 • The Functional Diversity of Native and Recombinant AMPA Receptors.- 12 • Electrophysiologic Characteristics of Heteromeric Recombinant NMDA Receptors: Comparison with Native Receptors.- 13 • Pharmacology of Recombinant NMDA Receptors: Possible Mechanisms for NMDA Receptor Heterogeneity.- 14 • On the Molecular Basis of NMDA Receptor Diversity.

Reviews

...will be an important reference...Each chapter is worth reading in its entirety, and each provides a solid groundingin the state of research to this point...will help [to] guide us over the next six years. - Journal of Molecular Neuroscience

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions