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OverviewThe Immune System: Mental Health and Neurological Conditions fully investigates how immune-related cellular, molecular, and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut microbiome and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. New chapters and sections on peripheral and central mechanisms in relation to viral pathogens, RNA editing to treat diseases, and COVID-19 will be included. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. This book covers both mental-health conditions and degenerative disorders of the brain, including depression, schizophrenia, autism-like spectrum disorders, Parkinson’s disease and Alzheimer’s-like dementia. Full Product DetailsAuthor: Hymie Anisman (Canada Research Chair in Behavioral Neuroscience, Department of Neuroscience, Carleton University, Ottawa, ONT, Canada) , Shawn Hayley (Health Sciences Building,Carleton University, Ottawa, Ontario, Canada) , Alexander W. Kusnecov (Professor, Behavioral and Systems Neuroscience Program, Department of Psychology, Rutgers University, Piscataway, NJ, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Edition: 2nd edition Weight: 0.450kg ISBN: 9780443235658ISBN 10: 0443235651 Pages: 598 Publication Date: 15 November 2024 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Forthcoming Availability: Not yet available  This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release. Table of Contents1. Multiple Pathways Linked to Mental Health and Illness 2. The Immune System: An Overview 3. Bacteria, Viruses, and the Microbiome 4. Lifestyle Factors Affecting Biological Processes and Health 5. Stressor Processes and Effects on Neurobiological Functioning 6. Stress and Immunity 7. Viral factors related to mental and neurological disorders 8. Prenatal and Early Postnatal Influences on Health 9. Depressive Disorders 10. Anxiety Disorders 11. Posttraumatic Stress Disorder 12. Pain Processes 13. Autism 14. Schizophrenia 15. Inflammatory Roads to Parkinson’s Disease 16. A Neuroinflammatory View of Alzheimer’s Disease 17. Comorbidities in Relation to Inflammatory processesReviewsAuthor InformationHymie Anisman received his PhD from the University of Waterloo, where he was also on faculty for two years, and has been a Professor at Carleton University, since 1994. He has also held an adjunct appointment with the Institute of Mental Health Research (Royal Ottawa Hospital) since 1993. Professor Anisman was a Senior Ontario Mental Health Research Fellow, is a Fellow of the Royal Society of Canada, and held a Canada Research Chair in Neuroscience from 2001-2015, and has since held the position of Canada Research Professor. The principle theme of his research has concerned the influence of stressors on neurochemical, neuroendocrine and immune systems, and how these influence psychological (anxiety, depression) and physical illnesses including neurodegenerative, heart disease, and cancer progression. Shawn Hayley is a Full Professor and previous Canada Research Chair in the Department of Neuroscience at Carleton University. Some of his research examines how the immune system influences neuroplasticity of the brain and consequently, how could be important for the development of new antidepressant drugs. As well, Dr. Hayley has been focused on how inflammation within the brain can cause neuronal degeneration and contribute to the onset and progression of Parkinson’s disease. The Hayley lab is involved in studies in assessing how chemical (e.g. pesticides) immunologic (e.g. viral, bacterial agents) and even psychological environmental stressors can contribute to the development of Parkinson's disease, as well as it comorbid states (e.g. depression, anxiety). Much of this research is focused on how the brain's specialized immune cells, the microglia, are involved in the generation of neuronal pathology, as well as possibly recovery from pathology. Alex Kusnecov received his doctorate from the University of Newcastle, New South Wales, Australia, after which he conducted postdoctoral research in psychoneuroimmunology at the University of Rochester. Subsequently, he held a faculty appointment in the Department of Pathology, University of Pittsburgh Medical Center, USA. He is currently a Professor within the Department of Psychology at Rutgers University, where his research involves the analyses of functional relationships between the brain and behavior, endocrine systems, and immune processes. His research on psychoneuroimmunology has appeared in prestigious journals, and together with Dr. Anisman, he has published two books (one an edited volume, and the other a text dealing with the involvement of the immune system in mental illnesses and neurodegenerative disorders). His research is funded by the National Institutes of Mental Health (NIMH). He serves on the editorial board of Brain, Behavior and Immunity, and has served on several National Institute for Health research grant panels, and has reviewed grants for Canadian and European grant agencies. He has acted as undergraduate director of the Department of Psychology, and currently co-chairs the Department of Psychology Diversity and Climate Committee. 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