Overview

The soil-transmitted nematode parasites, or geohelminths, are so called because they have a direct life cycle, which involves no intermediate hosts or vectors, and are transmitted by faecal contamination of soil, foodstuffs and water supplies. They all inhabit the intestine in their adult stages but most species also have tissue-migratory juvenile stages, so the disease manifestations they cause can therefore be both local and systemic. The geohelminths together present an enormous infection burden on humanity. Those which cause the most disease in humans are divided into three main groupings, Ascaris lumbricoides (the large roundworm), Trichuris trichiura (whipworm), and the blood-feeding hookworms (Ancylostoma duodenale and Necator americanus ). This text is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

Full Product Details

Author:   Celia V. Holland ,  Malcolm W. Kennedy
Publisher:   Springer
Imprint:   Springer
Edition:   2002 ed.
Volume:   2
Dimensions:   Width: 15.50cm , Height: 2.00cm , Length: 23.30cm
Weight:   0.699kg
ISBN:  

9780792375579

ISBN 10:   0792375572
Pages:   335
Publication Date:   31 December 2001
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Epidemiological Patterns and Consequences.- Distributions and Predisposition: People and Pigs.- Control Strategies.- The Cost and the Damage Done.- Pathophysiology of Intestinal Nematodes.- Intestinal Nematodes and Cognitive Development.- The Economics of Worm Control.- Immunology — Mice, Pigs and People.- Immune Responses on Humans — Ascaris.- Immunity and Immune Responses to Ascaris Suum in Pigs.- Immune Responses in Humans — Trichuris trichiura.- The Immunobiology of Hookworm Infection.- Genetics — Mice, Worms and People.- Human Host Susceptibility to Intestinal Worm Infections.- Population Genetics of Intestinal Nematodes.- Parasite Strain Diversity and Host Immune Responses.- The Value of Mutation Scanning Approaches for Detecting Genetic Variation — Implications for Studying Intestinal Nematodes of Humans.- Opportunities and Prospects for Investigating Developmentally Regulated and Sex-Specific Genes and Their Expression in Intestinal Nematodes of Humans.- Interaction between Geohelminth Infections and Other Diseases.- Schistosomiasis and Reduced Risk of Atopic Diseases: New Insights and Possible Mechanisms.- Geohelminths, HIV/AIDS and TB.

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