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OverviewTwo polymorphisms found within the CTLA4 gene were studied amongst a sample of coeliac patients and cord blood DNA samples that acted as the control group. Polymorphisms within the CTLA4 gene have been associated with other autoimmune conditions and the gene plays a very important role in immuno-regulatory function. The coeliac individuals and cord blood samples were genotyped for the -318 C/T and +49 A/G single nucleotide polymorphisms. No association of the single polymorphisms or the combined haplotypes with the coeliac condition was apparent amongst the coeliac patients under study. The -318 C allele and the +49 A allele were in linkage disequilibrium amongst the cord blood samples. Full Product DetailsAuthor: Joseph Borg , Angela A Xuereb Christopher Vidal , Christian A ScerriPublisher: LAP Lambert Academic Publishing Imprint: LAP Lambert Academic Publishing Dimensions: Width: 15.20cm , Height: 0.70cm , Length: 22.90cm Weight: 0.177kg ISBN: 9783838367422ISBN 10: 3838367421 Pages: 112 Publication Date: 27 May 2010 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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