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OverviewAs the active interface of the most biologically intimate connection between two living organisms, a mother and her fetus, the placenta is crucial to human evolution and survival. Michael L. Power and Jay Schulkin explore the more than 100 million years of evolution that led to the human placenta and, in so doing, they help unravel the mysteries of human life's first moments. Starting with some of the earliest events that have influenced the path of placental evolution in mammals and progressing to the specifics of the human placenta, this book examines modern gestation within an evolutionary framework. Human beings are a successful species and our numbers have increased dramatically since our earliest days on Earth. However, human fetal development is fraught with poor outcomes for both the mother and fetus that appear to be, if not unique, far more common in humans than in other mammals. High rates of early pregnancy loss, nausea and vomiting during pregnancy, preeclampsia and related maternal hypertension, and preterm birth are rare or absent in other mammals yet not unusual in humans. Power and Schulkin explain why this apparent contradiction exists and address such topics as how the placenta regulates and coordinates the metabolism, growth, and development of both mother and fetus, the placenta's role in protecting a fetus from the mother's immune system, and placental diseases. In the process, they reveal the vital importance of this organ-which is composed mostly of fetal cells-for us as individuals and as a species. Full Product DetailsAuthor: Michael L. Power (Senior Research Associate, American Congress of Obstetricians and Gynecologists) , Jay Schulkin (Director, The American Congress of Obstetricians and Gynecologists)Publisher: Johns Hopkins University Press Imprint: Johns Hopkins University Press Dimensions: Width: 15.20cm , Height: 2.40cm , Length: 22.90cm Weight: 0.499kg ISBN: 9781421406435ISBN 10: 1421406438 Pages: 280 Publication Date: 27 December 2012 Recommended Age: From 17 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: To order Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us. Table of ContentsIntroduction 1. The History of Placental Investigations 2. The Evolution of Live Birth in Mammals 3. Comparative Mammalian Placentation 4. The Evolution of the Human Placenta 5. Sex and the Placenta 6. Genes, Genetic Regulation, and the Placenta 7. The Placenta as a Regulatory Organ 8. Modern Gestational Challenges Conclusion References IndexReviewsThis reveals the importance of this organ for individuals and the species as a whole, and is recommended for science and health holdings alike. Midwest Book Review 2013 This reveals the importance of this organ for individuals and the species as a whole, and is recommended for science and health holdings alike. * Midwest Book Review * This reveals the importance of this organ for individuals and the species as a whole, and is recommended for science and health holdings alike. Midwest Book Review Author InformationMichael L. Power and Jay Schulkin are researchers at the American College of Obstetricians and Gynecologists in Washington, D.C. Together they authored The Evolution of Obesity, also published by Johns Hopkins. Tab Content 6Author Website:Countries AvailableAll regions |