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Author:   Cheryl S. Rosenfeld (Professor, Department of Biomedical Sciences, University of Missouri, Columbia, MO, United States)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 19.10cm , Height: 2.50cm , Length: 23.50cm
Weight:   1.130kg
ISBN:  

9780128013830

ISBN 10:   0128013834
Pages:   560
Publication Date:   23 October 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. The Developmental Origins of Health and Disease (DOHaD) concept: past, present and future. 2. Historical Perspective of Developmental Origins of Health and Disease in Humans 3. DOHaD and the Periconceptional Period, a Critical Window in Time 4. Introduction to Epigenetic Mechanisms: The Probable Common Thread for Various Developmental Origins of Health and Diseases Effects 5. Fetal Neuro-Hormonal Programming and Endocrine Disruption 6. Parental nutrition and developmental origins of health and disease 7. Maternal prenatal stress and the developmental origins of mental health: the role of epigenetics 8. Epigenetics in the Developmental Origin of Cardiovascular Disorders 9. Developmental Effects of Endocrine-Disrupting Chemicals in the Ovary and on Female Fertility 10. Developmental and Epigenetic Origins of Male Reproductive Pathologies 11. Developmental Origins of Childhood Asthma and Allergic Conditions – is there evidence of epigenetic regulation? 12. Immune Disorders, Epigenetics, and the Developmental Origins of Health and Disease 13. Neurobehavioral Disorders and DOHaD 14. Metabolic Disorders and DOHaD 15. The developmental origins of renal dysfunction 16. Cancer and DOHaD- Epigenetic reprogramming as a mediator 17. Epigenetic regulation of gastrointestinal epithelial barrier and developmental origin of health and disease 18. How the Father might Epigenetically Program the Risk for Developmental Origins of Health and Disease Effects in his Offspring 19. Linkage Between in Utero Environmental Changes and Preterm Birth 20. Sexual Dimorphism and DOHaD Through the Lens of Epigenetics 21. Transgenerational Epigenetic Inheritance: Past Exposures, Future Diseases 22. The Placenta and DOHaD 23. The Moral and Legal Relevance of DOHaD Effects for Pregnant Mothers 24. Introduction to Moms in Motion (MIM) Chapter 25. Reversing Harmful DOHaD Effects 26. Informational Resources for Developmental Origins of Health and Disease Research

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Author Information

Cheryl S. Rosenfeld, DVM, PhD, has published extensively on how maternal diet and developmental exposure to endocrine-disrupting compounds affect offspring outcomes. She has written several review articles and book chapters, including the most recent one on animal models of transgenerational epigenetic effects in Transgenerational Epigenetics: Evidence and Debate, published by Elsevier. She also edited and coauthored the book The Epigenome and Developmental Origins of Health and Disease, which won the BMA Medical Award for Basic and Clinical Sciences in 2016.

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