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OverviewA variety of new techniques that promise to revolutionize the clinical management of early pregnancy are fully detailed in this state-of-the-art book. Leading international researchers describe fast-moving topics such as embryo manipulation and the diagnosis of congenital abnormalities. The technology of assisted reproduction has made it possible to study living embryonic material for the first time, which has led to rapid advances in our understanding of the human embryo's early development. For example, study of the embryo in the test tube has pointed to early pregnancy loss as a possible cause of later infertility. Even more important, diagnostic tests using sophisticated techniques of molecular biology can be run on single cells before the embryo is replaced in the uterus. Another area of advance is the diagnosis of congenital abnormalities in the first and second trimesters of pregnancy. Great improvements have been made in the techniques of chorion villus biopsy and ultrasound imaging. A spectrum of simple biochemical tests performed on the mother's blood can greatly improve the detection of Down syndrome and other chromosome defects. Together with other developments in the fields of molecular biology and endocrinology, these new diagnostic techniques are the beginning of a new age in clinical human genetics and embryology. Full Product DetailsAuthor: Michael G. Chapman , J. Gedis Grudzinskas , Tim ChardPublisher: Springer London Ltd Imprint: Springer London Ltd Edition: Softcover reprint of the original 1st ed. 1991 Dimensions: Width: 17.00cm , Height: 1.40cm , Length: 24.20cm Weight: 0.487kg ISBN: 9781447118046ISBN 10: 1447118049 Pages: 263 Publication Date: 22 November 2011 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of Contents1 Mechanisms of Early Embryonic Loss In Vivo and In Vitro.- 2 Aetiology of Pregnancy Failure.- 3 Anembryonic Pregnancy.- 4 Embryonic Loss: Clinical Perspectives.- 5 Embryo Biopsy.- 6 Preimplantation Diagnosis by DNA Amplification.- 7 Transabdominal Chorion Villus Biopsy Versus Amniocentesis for Diagnosis of Aneuploidy: Safety Is Not Enough.- 8 The Role of Echography in the Diagnosis of Fetal Chromosomal Defects.- 9 Embryoscopy: An Evolving Technology for Early Prenatal Diagnosis.- 10 Sexing the Pre-embryo.- 11 Embryonic Development: The Origin of Neural Tube Defects.- 12 Ultrasound and Biochemical Assessment of First Trimester Pregnancy.- 13 Endocrinology and Metabolism in Early Pregnancy.- 14 The Endocrinology of the Fetoplacental Unit in the Second Trimester of Pregnancy.- 15 Endometrial Proteins.- 16 Maternal Serum AFP Screening for Fetal Malformations and Down’s Syndrome.- 17 Biochemical Screening for Down’s Syndrome.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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