The Chemical Synthesis of Peptides

Author:   John Jones (Lecturer in Organic Chemistry; Official Fellow and Tutor; Dean, Balliol College, Oxford)
Publisher:   Oxford University Press
Edition:   New edition
Volume:   23
ISBN:  

9780198558392


Pages:   240
Publication Date:   07 April 1994
Format:   Paperback
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

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The Chemical Synthesis of Peptides


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Overview

Peptides have diverse applications and potential in medicine. This book provides a critical, concise, and up-to-date survey of this field for graduates and experienced practitioners.

Full Product Details

Author:   John Jones (Lecturer in Organic Chemistry; Official Fellow and Tutor; Dean, Balliol College, Oxford)
Publisher:   Oxford University Press
Imprint:   Clarendon Press
Edition:   New edition
Volume:   23
Dimensions:   Width: 16.10cm , Height: 1.50cm , Length: 23.10cm
Weight:   0.412kg
ISBN:  

9780198558392


ISBN 10:   0198558392
Pages:   240
Publication Date:   07 April 1994
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   In Print   Availability explained
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

1. General introduction: Part I. Fundamental Chemical Principles 2: Introduction 3: *a-Amino-protection 4: *a-Carboxy-protection 5: Peptide bond formation 6: Residue specific considerations Part II: The Synthesis of Ordinary Peptides and Proteins 7: Strategy and tactics 8: Solution peptide synthesis 9: Solid phase peptide synthesis 10: Combined approaches and semisynthesis Part III: The Synthesis of Other Peptides 11: Conjugated peptides 12: Simple cyclopeptides 13: More complex modified peptides Epilogue Appendix A. Abbreviations and their uses Appendix B. A select bibliography and literature guide Index

Reviews

written with elegance and precision, by an expert in the area of peptide chemistry. Aimed at the research chemist, this book will be enjoyed by the expert while being invaluable to the less experienced. Pat Bailey in the Times Higher Education Supplement This is a good, plain, traditional book on the chemistry of peptide synthesis. ...will be especially valuable for new researchers who are contemplating or starting peptide synthesis ... I strongly recommend it. R. C. Sheppard in Chemistry in Britain an overview and appreciation of the field with a choice of language and literary skill which makes the text both intellectual and very pleasant to read ... highly commendable . Karl Folkers, Journal of the American Chemical Society


'This is a good, plain, traditional book on the chemistry of peptide synthesis. It is written in classical textbook style and is full of formulae, equations and flow sheets. ...will be especially valuable for new researchers who are contemplating or starting peptide synthesis ...a good book and I strongly recommend it.' Chemistry in Britain `This book is written with elegance and precision, by an expert in the area of peptide chemistry. Aimed at the research chemist, this book will be enjoyed by the expert while being invaluable to the less experienced. Times Higher Education Supplement 'the book offers a critical and up-to-date account of the chemical principles of peptide synthesis, and by limiting the subject matter it has been kept very compact ... a valuable aid for the newcomer to chemical methods of peptide synthesis ... Its main attraction is that practically every chapter is packed with a wealth of useful detail, a fact that even the specialist will only come to appreciate after studying it closely.' Hans-Dieter Jakubke, Angewandte Chemie, Vol. 31, No. 6, June 1992 'Dr. Jones prepared the text not only in a chronological and scientific style but also with an overview and appreciation of the field with a choice of language and literary skill which makes the text both intellectual and very pleasant to read. This book by Dr. John Jones is highly commendable.' Karl Folkers, The University of Texas at Austin, Journal of the American Chemical Society, Vol. 114, No. 22, 1992 'This book provides a critical, concise, and up-to-date survey of the area.' Evolutionary Aspects . Amino Acids, Peptides & Proteins, Vol. 21, No. 6' `The reprint of this excellent text published in 1991 contains a few corrections and several recent references. The excellent, well-documented selection of material and the lucid, concise, attractive presentation still apply to the reprint. Recommended to those requiring more detail than is available in textbooks of organic chemistry.' Aslib Book Guide, Vol. 50, No. 11, Nov 1994


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