Overview

Full Product Details

9781849737180

Table of Contents

Reviews

This book is 18th in a series on issues in toxicology. It is an excellent review of information relating to the potential carci- nogenicity of 27 metals and metalloid elements based on var- ious degrees of evidence from occupational, environmental, animals, and in vitro studies. The author does more than report the results; he evaluates the quality, relevance of the studies, and weight of the evidence of all the relevant data. For each metal, other useful information about natural occurrence, diet- ary levels, toxicity, and so on is listed. The possible mechanism of carcinogenesis is complex and the author does a good job of summarizing how genetic and epigenetic mechanisms are operational for the various metals. This book provides an excellent review of metal toxicity and occupational and environmental exposures related to mining and use of metals and would be useful in graduate courses in occupational medicine, toxicology, and carcinogenicity. It would also be a very useful resource to occupational physi- cians, toxicologists, industrial hygienists, environmental, and product safety specialists interested in metal carcinogenicity and occupational and environmental exposure to metals. This book is well written by an individual with an excellent knowl- edge of metal carcinogenicity and related occupational and environmental exposure. -- John J. Clary International Journal of Toxicology

This book is 18th in a series on issues in toxicology. It is an excellent review of information relating to the potential carci- nogenicity of 27 metals and metalloid elements based on var- ious degrees of evidence from occupational, environmental, animals, and in vitro studies. The author does more than report the results; he evaluates the quality, relevance of the studies, and weight of the evidence of all the relevant data. For each metal, other useful information about natural occurrence, diet- ary levels, toxicity, and so on is listed. The possible mechanism of carcinogenesis is complex and the author does a good job of summarizing how genetic and epigenetic mechanisms are operational for the various metals. This book provides an excellent review of metal toxicity and occupational and environmental exposures related to mining and use of metals and would be useful in graduate courses in occupational medicine, toxicology, and carcinogenicity. It would also be a very useful resource to occupational physi- cians, toxicologists, industrial hygienists, environmental, and product safety specialists interested in metal carcinogenicity and occupational and environmental exposure to metals. This book is well written by an individual with an excellent knowl- edge of metal carcinogenicity and related occupational and environmental exposure. -- John J. Clary International Journal of Toxicology ...an authoritative reference on the subject...The Carcinogenicity of Metals is a comprehensive and detailed overview of metal/metalloid toxicity and the risks of occupational or environmental exposure to such substances. It is written by an author who is clearly extremely knowledgeable about the subject matter...an excellent text for anybody interested in metals in toxicology and related occupational health and/or medicine at the graduate level and above. -- Dr Oliver Jones CBiol MSB The Biologist-the Society of Biology This book came along at just the right time for me: I was in the middle of writing a research paper on arsenic in soil and needed an authoritative reference on the subject, which is just what I found in this book. In fact, I could have been researching almost any metal or metalloid and it would have been useful. The Carcinogenicity of Metals is a comprehensive and detailed overview of metal/metalloid toxicity and the risks of occupational or environmental exposure to such substances. It is written by an author who is clearly extremely knowledgeable about the subject matter. Some of the metals, such as iron, zinc and lead, have chapters to themselves, others such as cadmium and mercury, and cobalt and nickel, are grouped together. In either case, the book describes the most up-to date research on the area in a clear and accessible way. Carcinogenicity is the linking theme and the author does a good job of summarising the many complex ways metals may cause this effect in living systems. For example, some elements may act on nucleic acids and/or affect gene expression, while others may cause oxidative stress, lipid peroxidation or changes in signal transduction. The book may be a little too specialised for undergraduate courses, but would be an excellent text for anybody interested in metals in toxicology and related occupational health and/or medicine at the graduate level and above. -- Dr Oliver Jones CBiol MSB The Biologist, The Society of Biology

Author Information

40 years research into the biology and pathology of the skin and its response to injury. Research into the nutrition and physiology of trace and xenbiotic metals in the skin. Study of intrinsic cytoprotective mechanisms against metal toxicity. Special studies onthe biological value of silver in wound care and as an antimicrobial agent in medical devices. International consultant and lecturer. Published 250 scientific papers and book chapters.

Tab Content 6

Customer Reviews

Recent Reviews

Countries Available