Free Delivery Over $100
|
|
|||
|
||||
OverviewFull Product DetailsAuthor: Anthony R. Rees (, Formerly Chief Scientific Officer (CSO) Biotage AB, Uppsala, Sweden (2010-2014))Publisher: Oxford University Press Imprint: Oxford University Press Dimensions: Width: 16.70cm , Height: 2.60cm , Length: 24.20cm Weight: 0.718kg ISBN: 9780199646579ISBN 10: 0199646570 Pages: 384 Publication Date: 30 October 2014 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1: Antibody pre-history: The emergence of empirical immunology 2: Pre-molecular immunology: The dawn of mechanism 3: Structural chemistry: Locks, keys and colloids 4: The foundations of antibody-antigen recognition emerge 5: The cellular reformation 6: The molecular path unfolds 7: Uncovering the origins of antibody diversity 8: Immunoglobulin constant regions 9: Effector functions of constant regions 10: Transmission and catabolism of IgG 11: The structural context of antibody diversity 12: Monoclonal antibodies and the mechanisms of hypermutation 13: Antibody structure prediction and development of humanization strategies 14: Antibody engineering: Improving on natural immunity 15: Therapeutic antibodies: Case study 1: Prevention of respiratory syncytial virus illness 16: Therapeutic antibodies: Case study 2: Targeting breast cancer 17: Antibodies: The therapeutic futureReviewsAn enjoyable read and I would thoroughly recommend it to anyone who wants to learn about the stories that lie behind the modern textbook understanding of the antibody molecule and its therapeutic applications. * Mike Clark, Reader in Therapeutic and Molecular Immunology (Retired), University of Cambridge; British Journal of Cardiology, 22 (25), 2015 * The Antibody Molecule is a marvelous synthesis of pertinent scientific literature from the late nineteenth century to the modern day, by someone who has an intimate firsthand knowledge of what it is like to have worked in this field. * - Neerja Sankaran, ISIS (A Journal of the History of Science Society) * An enjoyable read and I would thoroughly recommend it to anyone who wants to learn about the stories that lie behind the modern textbook understanding of the antibody molecule and its therapeutic applications. Mike Clark, Reader in Therapeutic and Molecular Immunology (Retired), University of Cambridge; British Journal of Cardiology, 22 (25), 2015 The Antibody Molecule is a marvelous synthesis of pertinent scientific literature from the late nineteenth century to the modern day, by someone who has an intimate firsthand knowledge of what it is like to have worked in this field. - Neerja Sankaran, ISIS (A Journal of the History of Science Society) An enjoyable read and I would thoroughly recommend it to anyone who wants to learn about the stories that lie behind the modern textbook understanding of the antibody molecule and its therapeutic applications. Mike Clark, Reader in Therapeutic and Molecular Immunology (Retired), University of Cambridge; British Journal of Cardiology, 22 (25), 2015 Author InformationAnthony Rees is currently Principle at Rees Consulting AB, Uppsala, Sweden. He was lecturer in Molecular Biophysics and Student of Christ Church from 1980 to 1990 at the University of Oxford. From 1990-1997 he was Professor and Head of the School of Biology and Biochemistry, University of Bath where he is an Emeritus Professor and holds an Honorary Doctor of Science. In 1989 he was a scientific cofounder with Graham Richards of Oxford Molecular, which became one of the earliest UK biotechnology companies to be listed on the London Stock Exchange. He has been visiting Professor at the Universities of Montpellier and Lund, scientific director of the French company Synt:em, CEO of the Swedish company MIP Technologies and Chairman of the Board of the antibody technology company, F-star. He is a member of the American Association for the History of Science and has published more than 120 scientific papers, a number of books and is an inventor on more than 30 patents. Tab Content 6Author Website:Countries AvailableAll regions |
||||
