Systems Biology: Simulation of Dynamic Network States

Author:   Bernhard Palsson
Publisher:   Not Avail
ISBN:  

9786613296146


Pages:   333
Publication Date:   26 May 2011
Format:   Electronic book text
Availability:   In stock   Availability explained
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Systems Biology: Simulation of Dynamic Network States


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Overview

Biophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard . Palsson shows how network reconstructions that are based on genomic and bibliomic data, and take the form of established stoichiometric matrices, can be converted into dynamic models using metabolomic and fluxomic data. The Mass Action Stoichiometric Simulation (MASS) procedure can be used for any cellular process for which data is available and allows a scalable step-by-step approach to the practical construction of network models. Specifically, it can treat integrated processes that need explicit accounting of small molecules and protein, which allows simulation at the molecular level. The material has been class-tested by the author at both the undergraduate and graduate level. All computations in the text are available online in MATLAB and MATHEMATICA workbooks, allowing hands-on practice with the material.

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Author:   Bernhard Palsson
Publisher:   Not Avail
Imprint:   Not Avail
ISBN:  

9786613296146


ISBN 10:   6613296147
Pages:   333
Publication Date:   26 May 2011
Audience:   General/trade ,  General
Format:   Electronic book text
Publisher's Status:   Active
Availability:   In stock   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

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