Systematic Approach to Evaluation of Mouse Mutations

Author:   John P. Sundberg ,  Dawnalyn Boggess
Publisher:   Taylor & Francis Inc
ISBN:  

9780849319051


Pages:   216
Publication Date:   23 July 1999
Format:   Hardback
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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Systematic Approach to Evaluation of Mouse Mutations


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Overview

Experts from The Jackson Laboratory and around the world provide practical advice on everything from how to establish a colony to where to go for specific mutations. The book includes information on medical photography, grafting procedures, and how to map the genes and evaluate the special biological characteristics of mice. It also discusses how to maintain a colony of mice that breed with difficulty, how to approach mapping spontaneous mutations, how to set up systems to evaluate a specific antibody, how to perform simple measurements that yield a large amount of information, and how to access mouse informatics on the Web.

Full Product Details

Author:   John P. Sundberg ,  Dawnalyn Boggess
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Dimensions:   Width: 15.60cm , Height: 1.70cm , Length: 23.40cm
Weight:   0.560kg
ISBN:  

9780849319051


ISBN 10:   0849319056
Pages:   216
Publication Date:   23 July 1999
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Mouse Colony Establishment-Determining the Genetic Basis of a New Trait-Xavier Montagutelli Computerized Colony Record Keeping-Medical Record Keeping for Project Analysis-Necropsy Methods for Laboratory Mice. Biological Characterization of a New Mutation- Photography of Mutant Laboratory Mice-Comparative Pathology and Animal Model Development-Kinetics and Morphometrics-Ultrastructural Evaluation of Mouse Mutations-Immunohistochemical and Immunofluoresence Methods-Radiolabeled cRNA and In Situ Hybridization-In Situ Hybridization with Non-Radiolabeled Probes-Repositories of Mouse Mutations and Inbred, Congenic and Recombitant Inbred Strains

Reviews

"""The Jackson Lab crew, with assists from other contributors, have put together a reference for scientists, mouse geneticists, managers and lab animal veterinarians. This new edition is a valuable reference for those involved with transgenic mice and mice colonies where specific mutations are maintained as research models."" -Mark Klinger in Laboratory Animal Practitioner"


The Jackson Lab crew, with assists from other contributors, have put together a reference for scientists, mouse geneticists, managers and lab animal veterinarians. This new edition is a valuable reference for those involved with transgenic mice and mice colonies where specific mutations are maintained as research models. -Mark Klinger in Laboratory Animal Practitioner


Author Information

John P. Sundberg, Dawnalyn Boggess

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