Overview

A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

Full Product Details

Author:   Mesut Karahan
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Weight:   0.453kg
ISBN:  

9780367700881

ISBN 10:   0367700883
Pages:   292
Publication Date:   26 September 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

"Chapter 1. Background Chapter 2. Introduction to Vaccination Chapter 3. Fundamentals of Modern Peptide Synthesis Chapter 4. Peptide Synthesis and Characterization Stages Chapter 5. Conjugation of Polymers with Biomolecules and Polymeric Vaccine Development Technologies Chapter 6. What are Polymeric Carriers? Chapter 7. Conjugation and Other Methods in Polymeric Vaccines Chapter 8. Polymeric Nanoparticle Preparation Methods Chapter 9. Peptides in Brain Disorders Chapter 10. Pseudo-proteins and related synthetic amino acid based polymers promising for constructing artificial vaccines Chapter 11. Peptide Vaccines in Cancer Diseases Chapter 12. Antioxidant Peptides Chapter 13. Peptide Vaccine Chapter 14. Adjuvants Of Vaccine in Immunotoxicology Chapter 15. Role of Epigenetics in Immunity and Immune Response to Vaccination Chapter 16. ""Omics"" technologies in vaccine research Chapter 17. Computer-Aided Epitope Identification and Design of Epitope Mimetics."

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Author Information

"Assoc. Prof. Dr. Mesut Karahan graduated from Yildiz Technical University, Faculty of Arts and Sciences Department of Chemistry in 1999. Between 2001 and 2012, Dr. Karahan worked in Yildiz Technical University. He got his master’s degree in 2002 at the same university with his study titled ""Ternary Polymer-Metal-Protein Complex Structure Models"". Assoc. Prof. Dr. Karahan completed his Ph.D. studies in 2009 on ""Development of Functional Biopolymer Systems Containing Metal”. He has been working at Üsküdar University since 2012. Working Areas: Vaccine Systems, Diagnostic Kit, Biochemistry, Biopolymer Systems, Peptide Synthesis, Proteins, Bioconjugation, Biopolymer-Metal-Peptide Complexes."

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