Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders

Author:   Maurizio Popoli ,  David Diamond ,  Gerard Sanacora
Publisher:   Springer-Verlag New York Inc.
Edition:   2014 ed.
ISBN:  

9781493910557


Pages:   355
Publication Date:   28 July 2014
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders


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Overview

Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive. Findings have shed new light on the mechanisms that determine the effects of stress on cognitive and affective function. Researchers have brought a wide range of techniques to bear on the study of this problem, including cutting-edge live imaging techniques, electrophysiology, glutamate release from isolated live synaptic terminals, development of transgenic and animal models and new behavioral methods. This book provides an overview of these recent findings and of the techniques used as well as a discussion of how the molecular, cellular, and functional effects of stress may trigger or precipitate neuropsychiatric disorders such as depression, schizophrenia, anxiety and PTSD.

Full Product Details

Author:   Maurizio Popoli ,  David Diamond ,  Gerard Sanacora
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2014 ed.
Dimensions:   Width: 15.50cm , Height: 2.20cm , Length: 23.50cm
Weight:   6.801kg
ISBN:  

9781493910557


ISBN 10:   1493910558
Pages:   355
Publication Date:   28 July 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

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Reviews

From the book reviews: This informative book, written and edited by an international array of well-known stress researchers, provides the latest information on the molecular mechanisms mediating stress in the pathogenesis of neuropsychiatric illnesses. ... The target audience includes bench neuroscientists and clinicians who want to learn about the latest research on fundamental neuroendocrine stress mechanisms and stress-related diseases. ... Each chapter ends with relevant and timely citations of the scientific literature. (Michael Joel Schrift, Doody's Book Reviews, January, 2015)


From the book reviews: This informative book, written and edited by an international array of well-known stress researchers, provides the latest information on the molecular mechanisms mediating stress in the pathogenesis of neuropsychiatric illnesses. ... The target audience includes bench neuroscientists and clinicians who want to learn about the latest research on fundamental neuroendocrine stress mechanisms and stress-related diseases. ... Each chapter ends with relevant and timely citations of the scientific literature. (Michael Joel Schrift, Doody's Book Reviews, January, 2015)


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