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OverviewThis book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing. Full Product DetailsAuthor: Marek ProchazkaPublisher: Springer International Publishing AG Imprint: Springer International Publishing AG Edition: 1st ed. 2016 Dimensions: Width: 15.50cm , Height: 1.40cm , Length: 23.50cm Weight: 4.853kg ISBN: 9783319239903ISBN 10: 3319239902 Pages: 221 Publication Date: 18 December 2015 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsIntroduction.- Basics of Raman scattering (RS) spectroscopy.- Basics of surface-enhanced Raman scattering (SERS).- Bioanalytical SERS applications.- Biomolecular SERS applications.- SERS investigations of cells, viruses and microorganisms.- Medical applications of SERS.- Conclusions and outlook.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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