Overview
Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Recent, significant improvements in instrumentation have rekindled interest in SFC and have enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its potential beyond traditional liquid chromatography, yet many of its capabilities remain underappreciated. Supercritical Fluid Chromatography and Extraction explores contemporary supercritical fluid chromatography and extraction and how it should be implemented in laboratory science for analysis, isolation, and production. New to This Edition This new edition details recent advances and applications of supercritical fluids in sample prep, instrumental analysis, and process-scale, including SFE, making it a comprehensive resource for both techniques. Further enhancements to this edition include: Expanded section on SFC theory to include gradient elution A new chapter on general detectors for SFC Enhanced method development coverage, with focus on gradient elution practices Includes multidimensional SFC, SFC × SFC, and LC-SFC Features comprehensive information on accelerated solvents, comparing solvent and extraction techniques. Highlights environmental monitoring and analysis applications of SFE. Widely used in the food industry for decades, SFE is now expanding into new fields. Supercritical Fluid Chromatography and Extraction, Second Edition serves as a valuable resource for chemical engineers, chemists, researchers, students, and academics working with supercritical fluids at preparative and process scales. It’s also an ideal introduction for newcomers to SFC and SFE.
Full Product Details
Author: Caroline West (Assistant Professor in Analytical Chemistry, University of Orléans, France) ,
Colin F. Poole (Department of Chemistry, Wayne State University, Detroit, MI, USA)
Publisher: Elsevier - Health Sciences Division
Imprint: Elsevier - Health Sciences Division
Edition: 2nd edition
ISBN: 9780443334696
ISBN 10: 0443334692
Pages: 660
Publication Date: 01 November 2025
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Paperback
Publisher's Status: Active
Availability: In Print
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.
Author Information
Caroline West received a PhD in Chemistry from the University of Paris-Saclay, France (2005) then was appointed as an Assistant Professor in analytical chemistry at the University of Orleans, France. She was later promoted to Full Professor (2020) in the same university. Her main scientific interests lie in fundamentals of chromatographic separation in liquids and supercritical fluids, both in achiral and chiral modes. She also applies these methods to different samples, such as pharmaceuticals and natural products. She is the author of over 100 papers, 7 book chapters, and has presented above 100 talks in national and international conferences and seminars. In 2015, she received the “LC‐GC Emerging Leader in Chromatography award from LC‐GC North America and was ranked several times among the most influential people in analytical chemistry by “The Analytical Scientist magazine (“Top 40 under 40 2014 & 2018, “The Power List 2019, 2020 & 2021). More recently, she was the recipient of the Jubilee medal from the Chromatographic Society (2021). Colin F. Poole was born and educated in the United Kingdom receiving a B.Sc. in Chemistry from the University of Leeds (1971) followed by graduate studies at the University of Bristol, MSc. in analytical chemistry (1972), and Ph.D. with Prof. E. D. Morgan at the University of Keele (1975) on the analysis of insect moulting hormones. Since 1980 he has been at the Department of Chemistry, Wayne State University, Detroit, Michigan, USA , except for 1995-1996, spent as the Governors’ Lecturer and Professor of Analytical Chemistry at Imperial College of Science, Technology & Medicine, London, in the United Kingdom. He is a former Science Advisor to the US Food and Drug Administration, a position he occupied for 25 years. Professor Poole has broad interests in the separation and detection of small molecules in biological, environmental, and food samples using a range of sample preparation, chromatographic and data analysis tools. He is the co-author of over 400 papers, 20 books, an editor of Journal of Chromatography A and a member of the editorial boards of 5 other analytical chemistry journals. .
