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OverviewStructure-function relationships of human pathogenic viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. In this volume, the relationship between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this title combines research data to provide a holistic view of viral pathogenesis. Full Product DetailsAuthor: Andreas Holzenburg , Elke BognerPublisher: Springer Science+Business Media Imprint: Kluwer Academic/Plenum Publishers Edition: 2002 ed. Dimensions: Width: 15.50cm , Height: 3.30cm , Length: 23.50cm Weight: 1.087kg ISBN: 9780306467684ISBN 10: 0306467682 Pages: 528 Publication Date: 30 April 2002 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: Out of stock The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsCell entry and egress.- Epstein Barr Virus Glycoproteins and their Roles in Virus Entry and Egress.- Structure and Function of Viral Glycoproteins in Membrane Fusion.- Viral replication.- Viral RNA-directed Polymerases: Structure and Function Relationships.- Marburg Virus Replication and Nucleocapsid Formation: Different Jobs, Same Players.- Viral determinants for capsid formation and packaging.- Packaging DNA into Herpesvirus Capsids.- From Concatemeric DNA into Unit-length Genomes—a Miracle or Clever Genes?.- Determinants for viral maturation.- Role of Envelope Proteins in Measles Virus Assembly.- The Predominant Varicella-zoster Virus gE and gI Glycoprotein Complex.- Expression Strategy and Functions of the Filoviral Glycoproteins.- Pathogenesis.- Prions.- Human Immunodeficiency Virus From Virus Structure to Pathogenesis.- The Role of Hemagglutinin and Neuraminidase in Influenza Virus Pathogenicity.- Viral oncogenesis.- Rhadinovirus Pathogenesis.- Interaction of Papillomaviral Oncoproteins with Cellular Factors.- Defense mechanisms.- Cytomegalovirus Glycoproteins Interacting with MHC Class I Molecules and the MHC-encoded Peptide Transporter.- Regulation of Cellular Genes by Cytomegalovirus.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |