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OverviewStructural genomics is the study of the DNA of living organisms. Evolutionary genomics is the study of the history of the genome. These subjects are closely interlinked. They are approached in this book using as a guideline the investigations carried out in the author's laboratory, relevant literature is critically reviewed and some general conclusions are presented. The author and his collaborators have studied a vast number of genomes, ranging from prokaryotes to human, using different approaches, including physical chemistry of DNA, viral integration and molecular cytogenetics. As the subtitle indicates the book discusses the fundamental importance of natural selection in shaping genomes. In terms of numbers, neutral and nearly neutral mutations represent most mutations, but a regional control is exerted by natural selection (essentially negative or purifying selection). A neo-selectionist model is proposed for genome evolution. Full Product DetailsAuthor: G. BernardiPublisher: Elsevier Science & Technology Imprint: Elsevier Science Ltd Dimensions: Width: 17.10cm , Height: 2.50cm , Length: 24.80cm Weight: 0.989kg ISBN: 9780444512550ISBN 10: 0444512551 Pages: 342 Publication Date: 01 January 2004 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: Out of stock The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |