Overview

The stress proteins or heat shock proteins were originally identified on the basis of their enhanced synthesis following stress. It is now clear, however, that they also play a key role in stressed cells and in specific human diseases. This book provides a comprehensive account of these proteins, emphasizing the functions of the different stress proteins in unstressed and stressed cells of different types, their regulation by stressful and non-stressful stimuli and their roles in a range of human diseases.

Full Product Details

Author:   David S. Latchman
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   1999 ed.
Volume:   136
Dimensions:   Width: 15.50cm , Height: 2.50cm , Length: 23.50cm
Weight:   0.916kg
ISBN:  

9783540650171

ISBN 10:   3540650172
Pages:   422
Publication Date:   26 November 1998
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

1 Stress Proteins: An Overview.- 2 The Hsp90 Chaperone Family.- 3 Heat Shock Protein 70.- 4 Mitochondrial Molecular Chaperones hsp60 and mhsp70: Are Their Roles Restricted to Mitochondria?.- 5 Role of Hsp27 and Related Proteins.- 6 Ubiquitin and the Stress Response.- 7 Regulation of Heat Shock Genes by Cytokines.- 8 Regulation of Heat Shock Genes by Ischemia.- 9 Regulation of Heat Shock Transcription Factors by Hypoxia or Ischemia/Reperfusion in the Heart and Brain.- 10 Autoregulation of the Heat Shock Response.- 11 The Cellular Stress Gene Response in Brain.- 12 Heat Stress Proteins and Their Relationship to Myocardial Protection.- 13 Heat Shock Proteins in Inflammation and Immunity.- 14 Heat Shock Proteins in Embryonic Development.- 15 Heat Shock Proteins in Rheumatoid Arthritis.- 16 Heat Shock Protein 60 and Type I Diabetes.- 17 Heat Shock Proteins and Multiple Sclerosis.- 18 Heat Shock Proteins in Atherosclerosis.- 19 Heat Shock Protein-Peptide Interaction: Basis for a New Generation of Vaccines Against Cancers and Intracellular Infections.

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