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OverviewThis volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control. Full Product DetailsAuthor: Moneeb EhteshamPublisher: Springer International Publishing AG Imprint: Springer International Publishing AG Edition: Softcover reprint of the original 1st ed. 2015 Volume: 853 Weight: 3.539kg ISBN: 9783319348513ISBN 10: 3319348515 Pages: 190 Publication Date: 09 October 2016 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsRegulation of Subventricular Zone-Derived Cells Migration in the Adult Brain.- The SVC and Its Relationship to Stem Cell Based Neuro-oncogenesis.- Isolation and characterization of stem cells for human central nervous system malignancies.- The role of stem cells in pediatric central nervous system malignancies.- Laboratory models for central nervous system tumor stem cell research.- Radiation Therapy for Glioma Stem Cells.- Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma.- Immunobiology and Immunotherapeutic targeting of glioma stem cells.- Emerging strategies for the treatment of tumor stem cells in central nervous system malignancies.ReviewsThis is an excellent textbook regarding the molecular and cell biology with respect to brain and spine neoplasms. This is a good book to look at and study if you are interested how cancer comes about. ... Research neurologists and neurosurgeons will find the book useful for their animal research. ... Graduate students, research fellows, and neuropathologists will be interested in the work presented here. (Joseph J. Grenier, Amazon.com, August, 2015) “This is an excellent textbook regarding the molecular and cell biology with respect to brain and spine neoplasms. This is a good book to look at and study if you are interested how cancer comes about. … Research neurologists and neurosurgeons will find the book useful for their animal research. … Graduate students, research fellows, and neuropathologists will be interested in the work presented here.” (Joseph J. Grenier, Amazon.com, August, 2015) Author Information"Moneeb Ehtesham, M.D. is a Principal Investigator at the Department of Neurological Oncology at Vanderbilt University Medical Center. His research focuses on cellular therapies on malignant gliomas. He has published over 30 peer-reviewed publications, 3 book chapters, and 38 peer-reviewed abstracts/presentations. He has received over 1260 citations. Dr. Ehtesham has been awarded the Young Investigator Award (2003) by the American Association of Neurological Surgeons & Congress of Neurological Surgeons. He's also been listed in ""Who's Who in Stem Cell Research"" by DataTrend Publications. Imad Khan, M.D. is a Research Associate at the Geisel School of Medicine at Dartmouth College. His research focuses on therapies for neurosurgical diseases and disorders. He has published over 30 peer-reviewed publications, 3 book chapters, and over 40 peer-reviewed abstracts/presentations." Tab Content 6Author Website:Countries AvailableAll regions |
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