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OverviewIn somatic cells, DNA is normally wrapped around the histones octamer to forms nucleosomes that eventually give rise to a solenoid DNA structure. Unlike somatic cells, in mammalian sperm, the development of spermatids into mature spermatozoa is accomplished by a series of structural and chemical modifications including a gradual replacement of lysine-rich histones by transition proteins and then by protamines which bind more tightly to DNA than histones, which results in compaction of chromatin in the sperm nucleus, a process which is termed 'sperm chromatin condensation'. This book examines the several techniques that have been devised in order to study chromatin and DNA defects in human spermatozoa. Full Product DetailsAuthor: Ali Reza TalebiPublisher: Nova Science Publishers Inc Imprint: Nova Science Publishers Inc Weight: 0.224kg ISBN: 9781616681944ISBN 10: 1616681942 Pages: 129 Publication Date: 21 October 2011 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsPreface; Part I. Mechanism of Sperm Nuclear Remodeling; Part II. The Origin of Sperm Chromatin/DNA Damages; Part III. Factors Affecting Sperm Chromatin & DNA Structure; Part IV. Sperm Chromatin/DNA Anomalies & Fertility; Index.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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