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OverviewReceptor tyrosine kinases are cell-surface receptors that respond to numerous hormones and growth factors, including insulin, insulin-like growth factors, epidermal growth factor, and nerve growth factor. They activate highly conserved intracellular signaling pathways that regulate cell proliferation, differentiation, and metabolism, playing essential roles in developing and adult animals. This book examines the nature of these receptors and their ligands, the molecular mechanisms that they regulate within cells, and the roles of the receptors in normal physiology and control of embryogenesis. It also discusses how dysfunction of these mechanisms can contribute to cancer and other diseases. Full Product DetailsAuthor: Joseph Schlessinger , Mark A LemmonPublisher: Cold Spring Harbor Laboratory Press,U.S. Imprint: Cold Spring Harbor Laboratory Press,U.S. Dimensions: Width: 18.50cm , Height: 2.50cm , Length: 25.90cm Weight: 1.202kg ISBN: 9781936113330ISBN 10: 1936113333 Pages: 478 Publication Date: 31 October 2013 Audience: General/trade , General Format: Hardback Publisher's Status: Active Availability: In stock  We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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