Signal Transduction: Pathways, Mechanisms and Diseases

Author:   Ari Sitaramayya
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Edition:   Softcover reprint of the original 1st ed. 2010
ISBN:  

9783662501917


Pages:   437
Publication Date:   23 August 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Signal Transduction: Pathways, Mechanisms and Diseases


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Overview

G Proteins and G Protein-Coupled Receptors.- Traditional GPCR Pharmacology and Beyond.- Regulation of Intraneuronal Trafficking of G-Protein-Coupled Receptors by Neurotransmitters In Vivo.- Small GTPases and Their Role in Regulating G Protein-Coupled Receptor Signal Transduction.- Regulation of G Protein Receptor Coupling, Mood Disorders and Mechanism of Action of Antidepressants.- Dysregulation of G Protein-Coupled Receptor Signaling in Cancer.- Growth Factors.- Insulin Signaling in Normal and Diabetic Conditions.- Epidermal Growth Factor (EGF) Receptor Signaling and Cancer.- Leptin Signaling Pathway.- Signaling in Normal and Pathological Angiogenesis.- Signaling Platforms.- Spatial and Temporal Control of Cell Signaling by A-Kinase Anchoring Proteins.- Mitochondria, a Platform for Diverse Signaling Pathways.- Mitogen-Activated Protein Kinases and Their Scaffolding Proteins.- Molecular and Functional Determinants of Ca2+ Signaling Microdomains.- Nuclear Receptors / Transcription.- Eukaryotic Gene Transcription.- Estrogen Signaling Mechanisms.- Signal Transduction Pathways Involved in Glucocorticoid Actions.- Reactive Signaling Molecules.- Cellular Signaling by Reactive Oxygen Species: Biochemical Basis and Physiological Scope.- Soluble Guanylyl Cyclase: The Nitric Oxide Receptor.- Cell Cycle, Cell Death and Cancer.- Distinct Roles of the Pocket Proteins in the Control of Cell Cycle.- Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis.- Aging and Cancer: Caretakers and Gatekeepers.- Signal Transduction in Embryonic Stem Cells and the Rise of iPS Cells.- Erratum to.

Full Product Details

Author:   Ari Sitaramayya
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 2010
Dimensions:   Width: 15.50cm , Height: 2.30cm , Length: 23.50cm
Weight:   0.924kg
ISBN:  

9783662501917


ISBN 10:   3662501910
Pages:   437
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

G Proteins and G Protein–Coupled Receptors.- Traditional GPCR Pharmacology and Beyond.- Regulation of Intraneuronal Trafficking of G-Protein-Coupled Receptors by Neurotransmitters In Vivo.- Small GTPases and Their Role in Regulating G Protein-Coupled Receptor Signal Transduction.- Regulation of G Protein Receptor Coupling, Mood Disorders and Mechanism of Action of Antidepressants.- Dysregulation of G Protein-Coupled Receptor Signaling in Cancer.- Growth Factors.- Insulin Signaling in Normal and Diabetic Conditions.- Epidermal Growth Factor (EGF) Receptor Signaling and Cancer.- Leptin Signaling Pathway.- Signaling in Normal and Pathological Angiogenesis.- Signaling Platforms.- Spatial and Temporal Control of Cell Signaling by A-Kinase Anchoring Proteins.- Mitochondria, a Platform for Diverse Signaling Pathways.- Mitogen-Activated Protein Kinases and Their Scaffolding Proteins.- Molecular and Functional Determinants of Ca2+ Signaling Microdomains.- Nuclear Receptors / Transcription.- Eukaryotic Gene Transcription.- Estrogen Signaling Mechanisms.- Signal Transduction Pathways Involved in Glucocorticoid Actions.- Reactive Signaling Molecules.- Cellular Signaling by Reactive Oxygen Species: Biochemical Basis and Physiological Scope.- Soluble Guanylyl Cyclase: The Nitric Oxide Receptor.- Cell Cycle, Cell Death and Cancer.- Distinct Roles of the Pocket Proteins in the Control of Cell Cycle.- Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis.- Aging and Cancer: Caretakers and Gatekeepers.- Signal Transduction in Embryonic Stem Cells and the Rise of iPS Cells.- Erratum to.

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