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OverviewSickle cell disease (SCD) is a group of inherited blood disorders. Sickle cell anemia (SCA) is the most common form of SCD. It is characterized by an abnormality in hemoglobin found in red blood cells. This results in rigid, sickle-shaped red blood cells. SCA typically develops symptoms like anemia, bacterial infections, stroke, pain, swelling in the hands and feet, etc. The gene defect associated with sickle cell disease is a single nucleotide mutation. Normal red blood cells are elastic thereby allowing cells to deform and pass through capillaries. In SCD, low oxygen tension promotes sickling of red blood cells which fail to return to the normal shape when the ideal oxygen tension is restored. These cells are therefore not able to pass through narrow capillaries, leading to ischemia and vessel occlusion. SCA can lead to complications such as stroke, severe bacterial infections, cholelithiasis, avascular necrosis, osteomyelitis, acute papillary necrosis, etc. This book is compiled in such a manner, that it will provide in-depth knowledge about the concerns and challenges in the management of sickle cell disease. It brings forth some of the most innovative concepts and elucidates the unexplored aspects of this disease. It is meant for students who are looking for an elaborate reference text on sickle cell disease. Full Product DetailsAuthor: Sabrina KelleyPublisher: Foster Academics Imprint: Foster Academics Dimensions: Width: 21.60cm , Height: 1.40cm , Length: 27.90cm Weight: 0.844kg ISBN: 9781632429230ISBN 10: 1632429233 Pages: 239 Publication Date: 22 September 2020 Audience: General/trade , General Format: Hardback Publisher's Status: Active Availability: In stock We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |