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Author:   Seunghee Cha
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
Edition:   Second Edition 2026
ISBN:  

9783032074577

ISBN 10:   3032074576
Pages:   300
Publication Date:   14 January 2026
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Part I. Updates on Salivary Gland Development.- 1. Implications of Salivary Gland Developmental Mechanisms for the Regeneration of Adult Damaged Tissues.- 2. Overview of Transcriptomic Approaches for the Study of Salivary Gland Biology and Regeneration.- 3. Mucins in Salivary Gland Development, Regeneration, and Disease with Special Emphasis on Sjögren’s Disease.- Part II. Glandular Damage and Cell Replacement Therapy.- 4. Histologic Changes in the Salivary Glands Following Radiation Therapy.- 5. Adult Stem Cell Therapy for Salivary Glands, with a Special Emphasis on Mesenchymal Stem Cells: An Update.- 6. Inductive Signals for Salivary Gland Regeneration.- Part III. Bioengineering of Salivary Glands.- 7. Emerging Trends in Salivary Gland Regeneration.-  8. Matrix Biology of the Salivary Gland: A Guide for Tissue Engineering.- 9. 3D Printing Technology in Craniofacial Surgery and Salivary Gland Regeneration.- 10. Functional Salivary Gland Regeneration by Organ Replacement Therapy.- Part IV. Therapeutic Considerations for Functional Salivary Gland Restorations.- 11. Regulation of Salivary Secretion.- 12. Salivary Gland Gene Therapy in Experimental and Clinical Trials.- 13. Surgical Management of Salivary Gland Diseases.

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Author Information

Seunghee Cha, DDS, PhD, is a Professor of Oral & Maxillofacial Diagnostic Sciences at the University of Florida College of Dentistry. Dr. Cha is actively involved in basic and clinical science research while attending patients and serving in leadership roles for various international scientific communities. She was the former President of the Salivary Research Group of the American/International Association for Dental Research and currently oversees research and patient care as the Director of the Center for Orphaned Autoimmune Disorders. Dr. Cha’s research focuses on the pathogenesis of autoimmune Sjӧgren’s disease (SS-> SjD) and cell replacement therapy to improve dry mouth in SS ->SjD patients. In particular, she has investigated the pathological roles of anti-muscarinic type 3 receptor autoantibodies in hyposalivation, epigenetic regulation of microRNA and its functions in innate immunity, self-nucleic acid sensing mechanisms in monocytes,  susceptibility genes by high-throughput genomics and proteomics, and diagnostic and therapeutic strategies for SS-> SjD. Dr. Cha has published extensively in peer-reviewed international journals.

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