Overview

RNA-protein interactions play a vital role in gene transcription and protein expression. Interactions such as the synthesis of mRNA by RNA polymerases, to the essential modification of RNA by the proteins of the spliceosome complex, and the highly-catalytic action of the ribosome in protein synthesis, are established as being fundamental to the function of RNA. Recent research into, for example, the role of RNA as a catalyst, has elucidated many more interactions with proteins that are vital to cell function. This text provides a guide to the experimental procedures used in studying RNA-protein interactions. The approaches covered range from those initially used to detect a novel RNA-protein interaction, various biochemical and genetic approaches to purifying and cloning RNA binding proteins, through to methods for an in-depth analysis of the structural basis of the interaction.

Full Product Details

Author:   Christopher B. R. Smith
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Volume:   No.192
Dimensions:   Width: 15.00cm , Height: 2.30cm , Length: 23.00cm
Weight:   0.736kg
ISBN:  

9780199636518

ISBN 10:   0199636516
Pages:   320
Publication Date:   01 September 1998
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   To order  
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