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OverviewThe presence of modified nucleotides in cellular RNAs has been known for decades and over 100 distinct RNA modifications have been characterized to date. While the exact role of many of these modifications is still unclear, many are highly conserved across evolution and most contribute to the overall fitness of the organism. In recent years, new methods and bioinformatics approaches have been developed for the dissection of modification pathways and functions. These methods intersect a number of related fields, ranging from RNA processing to comparative genomics and systems biology. In addition, many of the techniques described in this volume have broad applicability, particularly in regards to the isolation, characterization, and reconstitution of ribonucleoprotein complexes, expanding the experimental repertoire available to all RNA researchers. Full Product DetailsAuthor: Jonatha M. Gott (Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, Ohio, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Edition: 425th edition Volume: 425 Dimensions: Width: 15.20cm , Height: 2.40cm , Length: 22.90cm Weight: 0.770kg ISBN: 9780123741554ISBN 10: 0123741556 Pages: 480 Publication Date: 13 September 2007 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Out of stock  The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsReviewsAuthor InformationJonatha Gott works in the Center for RNA Molecular Biology at Case Western Reserve University, Cleveland, Ohio, USA. Tab Content 6Author Website:Countries AvailableAll regions |
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