RNA and DNA Diagnostics

Author:   Volker A. Erdmann ,  Stefan Jurga ,  Jan Barciszewski
Publisher:   Springer International Publishing AG
Edition:   2015 ed.
ISBN:  

9783319173047


Pages:   349
Publication Date:   29 June 2015
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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RNA and DNA Diagnostics


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Overview

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman’s famous statement “What I cannot create, I do not understand.”

Full Product Details

Author:   Volker A. Erdmann ,  Stefan Jurga ,  Jan Barciszewski
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   2015 ed.
Dimensions:   Width: 15.50cm , Height: 2.10cm , Length: 23.50cm
Weight:   6.623kg
ISBN:  

9783319173047


ISBN 10:   3319173049
Pages:   349
Publication Date:   29 June 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.
Language:   English

Table of Contents

Electrochemical Biosensors for miRNA Detection.- Electrochemical Detection of RNA.- DNA and PNA probes for DNA Detection in Electroanalytical Systems.- DNA for Non-Nucleic Acid Sensing.- Aptamers in Oncotherapy.- Genotyping of Single Nucleotide Polymorphism.- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA.- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics.- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures.- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods.- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics.- Mechanochemical Sensing.- Microarrays as Research Tools and Diagnostic Devices.- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.- Single-molecule strategies for DNA and RNA diagnostics.- Detection and Assessment of microRNA Expression in Human Disease.

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