Overview

Dr Spirin is a world authority on ribosomes and has published two earlier books in this area in English. This text is for advanced undergraduates and new graduate students and covers the structure, function, and biosynthesis of ribosomes. Ribosomes are important in protein synthesis, which is currently a hot topic in many different areas of research.

Full Product Details

Author:   Alexander Spirin
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   Softcover reprint of the original 1st ed. 1999
Dimensions:   Width: 17.80cm , Height: 2.30cm , Length: 25.40cm
Weight:   0.824kg
ISBN:  

9780306461460

ISBN 10:   0306461463
Pages:   416
Publication Date:   23 March 2000
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

I Historical and Fundamental Introduction.- 1 Protein Biosynthesis: Summary and Definitions.- 2 Messenger RNA and the Genetic Code.- 3 Transfer RNA and Aminoacyl-tRNA Synthetases.- 4 Ribosomes and Translation.- II Structure of the Ribosome.- 5 Morphology of the Ribosome.- 6 Ribosomal RNA.- 7 Ribosomal Proteins.- 8 Mutual Arrangement of Ribosomal RNA and Proteins (Quaternary Structure).- III Function of the Ribosome.- 9 Functional Activities and Functional Sites of the Ribosome.- 10 Elongation Cycle, Step I: Aminoacyl-tRNA Binding.- 11 Elongation Cycle, Step II: Transpeptidation (Peptide Bond Formation).- 12 Elongation Cycle, Step III: Translocation.- 13 Elongation Rate and Its Modulation.- 14 Termination of Translation.- 15 Initiation of Translation.- 16 Translational Control in Prokaryotes.- 17 Translational Control in Eukaryotes.- 18 Cotranslational Folding and Transmembrane Transport of Proteins.- 19 Conclusion: General Principles of Ribosome Structure and Function.

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