Free Delivery Over $100
|
|
|||
|
||||
OverviewRGS Protein Physiology and Pathophysiology describes the current, state-of-the-art research occurring in the laboratories of leaders in the RGS protein field that utilize genetic mouse models to interrogate the function of RGS proteins in vivo. Each chapter describes the elucidated role of a specific RGS protein or family of RGS proteins in normal physiology and/or disease with particular emphasis on how these discoveries inform healthcare and drug discovery. The work is a timely reference as drugs targeting G protein coupled receptors represent 40% of currently marketed therapeutics. Full Product DetailsAuthor: Rory A. Fisher (University of Iowa, Iowa City, IA, USA)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Volume: 133 Dimensions: Width: 15.20cm , Height: 1.50cm , Length: 22.90cm Weight: 0.540kg ISBN: 9780128029381ISBN 10: 0128029382 Pages: 226 Publication Date: 23 June 2015 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Manufactured on demand  We will order this item for you from a manufactured on demand supplier. Table of ContentsIntroduction: G Protein-coupled Receptors and RGS Proteins Adele Stewart and Rory A. Fisher RGS-insensitive G Proteins as in vivo Probes of RGS Function Richard R. Neubig RGS Protein Regulation of Phototransduction Ching-Kang Jason Chen Role of Regulators of G Protein Signaling (RGS) Proteins in Bone Physiology and Pathophysiology Joel Jules, Shuying Yang, Wei Chen and Yi-Ping Li Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function Patrick Osei-Owusu and Kendall J. Blumer Keeping the Balance Right: Regulator of G Protein Signaling 5 in Vascular Physiology and Pathology Ruth Ganss Two for the Price of One: G Protein-Dependent and -Independent Functions of RGS6 in vivo Adele Stewart, Biswanath Maity and Rory A. Fisher Physiology of RGS10 in Neurons and Immune Cells Jae-Kyung Lee and Malú G. Tansey Regulator of G Protein Signaling 14 (RGS14): A Molecular Brake for Synaptic Plasticity Linked to Learning and Memory Paul R. Evans, Serena M. Dudek and John R. HeplerReviewsAuthor InformationDr. Fisher is a 1983 graduate of Iowa State University (Ph.D.), who performed post-doctoral research at the University of Texas Health Science Center, San Antonio, before joining the faculty in Pharmacology at the University of Iowa in 1987. He was promoted to associate professor in 1993 and to professor in 2004. He has a secondary appointment in the Department of Internal Medicine and is a member of the Molecular and Cellular Biology interdisciplinary graduate program, the Holden Cancer Center, the Medical Scientist Training Program, and the Gene Therapy Center. His research focuses on the biology and signaling of RGS proteins and G proteins. He has served on numerous NIH study sections and his funding includes an R01 to study novel actions of RGS6 in tumor suppression and DNA damage signaling. Tab Content 6Author Website:Countries AvailableAll regions |
||||
