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Author:   Helge Großhans
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2010
Volume:   700
Dimensions:   Width: 17.80cm , Height: 1.50cm , Length: 25.40cm
Weight:   0.543kg
ISBN:  

9781441978226

ISBN 10:   1441978224
Pages:   160
Publication Date:   10 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

microRNA Biogenesis and Function.- Regulation of pri-miRNA Processing Through Smads.- Stimulation of pri-miR-18a Processing by hnRNP A1.- KSRP Promotes the Maturation of a Group of miRNA Precuresors.- Hormonal Repression of miRNA Biosynthesis Through a Nuclear Steroid Hormone Receptor.- Autoregulatory Mechanisms Controlling the Microprocessor.- Regulation of pre-miRNA Processing.- The Effect of RNA Editing and ADARs on miRNA Biogenesis and Function.- miRNAs Need a Trim.- Properties of the Regulatory RNA-Binding Protein HuR and its Role in Controlling miRNA Repression.- Turnover of Mature miRNAs and siRNAs in Plants and Algae.- MicroRNases and the Regulated Degradation of Mature Animal miRNAs.

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Author Information

Helge Großhans, PhD is a research group leader at the Friedrich Miescher Institute for Biomedical Research (FMI), which is part of the Novartis Research Foundation in Basel, Switzerland. His main research interests are in the developmental function, regulation, and mechanism of action of microRNAs. He received his PhD from the University of Heidelberg and did his postdoctoral training at Yale University. He is the winner of a 2009 ERC Award.

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