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OverviewPlease note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In the field of reverse genetics RMCE (recombinase-mediated cassette exchange) is of increasing relevance. The procedure permits the systematic, repeated modification of higher eukaryotic genomes by targeted integration. For RMCE, this is achieved by the clean exchange of a preexisting gene cassette for an analogous cassette carrying the gene of interest (GOI). The genetic modification of mammalian cells is a standard procedure for the production of correctly modified proteins with pharmaceutical relevance. To be successful, the transfer and expression of the transgene has to be highly efficient and should have a largely predictable outcome. Actual approaches in the field of gene therapy are based on the same principles. Full Product DetailsAuthor: Dagda Tanner MattheusPublisher: Duc Imprint: Duc Dimensions: Width: 15.20cm , Height: 0.90cm , Length: 22.90cm Weight: 0.239kg ISBN: 9786139269419ISBN 10: 6139269415 Pages: 156 Publication Date: 01 January 2012 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: Not yet available  This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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