Overview

Anemia is a frequent complication of cancer and its treatment. It produces many symptoms and significantly impairs metabolic and physiologic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. This book, now being published in its second edition, comprehensively presents the current knowledge on anemia in cancer and its treatment with rhEPO. Future developments are also discussed. Based on updated and new chapters, including a broader spectrum of topics, outstanding international experts describe the scientific and clinical aspects of anemia in various fields of oncology and give diagnostic and therapeutic recommendations on when and how to use rhEPO. The book, considered as a standard work, will again serve as an essential source of information for radiotherapists, medical oncologists, hematologists, internists, pediatricians, surgeons, specialists in transfusion and laboratory medicine, and pharmacologists.

Full Product Details

Author:   Mohammad Resa Nowrousian
Publisher:   Springer Verlag GmbH
Imprint:   Springer Verlag GmbH
Edition:   Softcover reprint of the original 2nd ed. 2008
Weight:   1.478kg
ISBN:  

9783709119044

ISBN 10:   3709119049
Pages:   866
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Physiology of erythropoiesis.- Biology of EPO.- EPO and EPO-receptor expression in tumor cells and their functional role.- Classification and characterization of anemia in cancer.- Pathophysiology of cancer-related and chemotherapy-induced anemia.- Prevalence, incidence, and treatment of anemia in cancer patients.- Prognostic significance of anemia in cancer chemotherapy.- Incidence and impact of anemia in radiation oncology.- Relationship between anemia and tumor hypoxia.- Tumor hypoxia and therapeutic resistance.- Symptomatology of anemia.- Impact of anemia on organ functions.- Relationship of hemoglobin, fatigue, and quality of life in anemic cancer patients.- Red blood cell transfusions, risks and limitations.- Pharmacology, pharmacokinetics and safety of rhEPO.- rhEPO in anemia associated with multiple myeloma and non-Hodgkin lymphoma.- rhEPO in myeloid disorders.- rhEPO in anemia associated with solid tumors and chemotherapy.- Predictive factors for response of anemia to rhEPO.- rhEPO in hematopoietic stem cell mobilization, transplantation, and in-vitro expansion.- rhEPO in radiation oncology.- rhEPO in pediatric oncology.- rhEPO in surgical oncology.- Erythropoiesis, iron metabolism and iron supplementation during treatment with rhEPO.- Optimal level of hemoglobin in cancer patients.- Metabolic and physiologic effects of rhEPO in anemic cancer patients.- Effects of rhEPO on quality of life in anemic cancer patients.- Effect of rhEPO on survival in anemic cancer patients.- Neuroprotective effects of erythropoietin.- Effects of rhEPO in patients with anemia and chronic heart failure.- Current status and future developments of rhEPO in clinical oncology.

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions