Overview

This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.

Full Product Details

Author:   Alfred Wittinghofer
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2014
Dimensions:   Width: 15.50cm , Height: 1.60cm , Length: 23.50cm
Weight:   4.628kg
ISBN:  

9783319378084

ISBN 10:   3319378082
Pages:   298
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Prenylation of RabGTPases, their delivery to membranes and Rab recycling.- Rab proteins and the organization of organelle membrane domains.- Effectors of Rab GTPases: Rab binding specificity and their role in coordination of Rab function and localization.- A Rab effector called the exocyst and related vesicle tether complexes.- RabGEFs and GAPs – the enigma variations.- Ran in Nucleocytoplasmic Transport.- Ran in Mitosis.- Arf proteins and their regulators: at the interface between membrane lipids and the protein trafficking machinery.- Small G Proteins: Arf family GTPases in vesicular transport.- ARF-LIKE (ARL) Proteins.- GTPase-Activating Proteins for the Arf-family Small GTPases: not only for the termination.- Rag GTPases.

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