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OverviewRadiochemical methodology constitutes the most important base for the successful functioning of a PET group in the routine production and development of radiopharmaceuticals. Of the several hundred products which have been labelled with positron emitters during the past two decades about 35 are presently considered to be of major interest. The time for a state-of-the-art review is right, since this field has advanced over the past fifteen years to reach a level where guidelines can now be suggested. Chapters of this book deal with each of the main methodological aspects of the chemistry needed to develop an effective radiopharmaceutical, namely radionuclide production, automation and metabolite analysis. A further chapter on QA/QC is written by a broadly-based expert group and is meant to provide a guideline and a base for future monographs and regulations on major PET radiopharmaceuticals of today. This book will help the increasing numbers of scientists who are now entering the field of PET to appreciate the methodological aspects that are normally addressed by chemists in relation to PET radiopharmaceuticals; it provides many useful practical guidelines and will promote early success in their own endeavours, since these will often necessarily begin by establishing chemical methodology of the kind discussed here. Full Product DetailsAuthor: G. Stöcklin , V.W. PikePublisher: Springer Imprint: Springer Edition: Softcover reprint of hardcover 1st ed. 1993 Volume: 24 Dimensions: Width: 16.00cm , Height: 1.00cm , Length: 24.00cm Weight: 0.454kg ISBN: 9789048142859ISBN 10: 9048142857 Pages: 180 Publication Date: 06 December 2010 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Out of stock  The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of Contents1. PET radionuclide production.- Appendix 1. Sources of 18O-enriched water.- 2. Radiochemistry automation for PET.- Appendix 1. Radioactivity detectors.- Appendix 2. Selection criteria for remotely operated valves used in PET chemistry.- Appendix 3. Sources of glassy carbon vessels.- 3. Quality assurance and quality control of short-lived radiopharmaceuticals for PET.- Appendix 1. Sources of precursors and standards for QA/QC.- 4. PET radiopharmaceutical metabolism — plasma metabolite analysis.Reviews'I highly recommend this book to the growing number of scientists involved in the production and development of positron-emitting radiopharmaceuticals ...' European Journal of Nuclear Medicine, 21:1 'I can equivocally recommend this book as essential reading for all persons involved in PET radiopharmaceutical production. No PET radiochemist/radiopharmacist should be without a copy on their lab-bench, office desk, and restroom library.' Clinical Nuclear Medicine, 19, 1994 'I highly recommend this book to the growing number of scientists involved in the production and development of positron-emitting radiopharmaceuticals ...' European Journal of Nuclear Medicine, 21:1 'I can equivocally recommend this book as essential reading for all persons involved in PET radiopharmaceutical production. No PET radiochemist/radiopharmacist should be without a copy on their lab-bench, office desk, and restroom library.' Clinical Nuclear Medicine, 19, 1994 Author InformationTab Content 6Author Website:Countries AvailableAll regions |
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