Quadruplex Nucleic Acids

Author:   Stephen Neidle (University of London, UK) ,  Shankar Balasubramanian (University of Cambridge, UK) ,  William A Harrell Jr (University of Maryland) ,  Simon Campbell
Publisher:   Royal Society of Chemistry
Volume:   Volume 7
ISBN:  

9780854043743


Pages:   301
Publication Date:   20 October 2006
Format:   Hardback
Availability:   In Print   Availability explained
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Quadruplex Nucleic Acids


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Author:   Stephen Neidle (University of London, UK) ,  Shankar Balasubramanian (University of Cambridge, UK) ,  William A Harrell Jr (University of Maryland) ,  Simon Campbell
Publisher:   Royal Society of Chemistry
Imprint:   Royal Society of Chemistry
Volume:   Volume 7
Dimensions:   Width: 15.60cm , Height: 2.10cm , Length: 23.40cm
Weight:   0.627kg
ISBN:  

9780854043743


ISBN 10:   0854043748
Pages:   301
Publication Date:   20 October 2006
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Fundamentals of Quadruplex Structures Stephen Neidle and Shankar Balasubramanian; Energetics, Kinetics and Dynamics of Quadruplex Folding; Structural Diversity of G-Quadruplex Scaffolds; The Role of Cations in Determining Quadruplex Structure and Stability; DNA Quadruplex–Ligand Recognition: Structure and Dynamics; Quadruplex Ligand Recognition: Biological Aspects; Quadruplexes and Gene Regulation; Quadruplexes in the Genome; Quadruplexes and the Biology of G-Rich Genomic Regions; The G-Quartet in Supramolecular Chemistry and Nanoscience

Reviews

A very useful resource that is an up-to-date record of the state of the field...I am sure that this book will remain as a useful resource for many years. ChemBioChem, 2008, 9, 642-645 (Keith Fox) Quadruplex Nucleic Acids, edited by Stephen Neidle and Shankar Balasubramanian, contains the most up-to-date information in this rapidly growing field, written by worldclass experts. It is an impressive fusion of knowledge, in a format volume of 297 pages, conveniently split into ten chapters. In summary, I believe Quadruplex Nucleic Acids provides a very comprehensive and up-to-date overview of chemical, physical and biological properties of G-quadruplex structures. The book not only covers these topics and concepts seamlessly, but also leaps into future directions, discussing potential applications of such structures in nanoscience and supramolecular chemistry. I thoroughly enjoyed reading this well-written and structured book and broadening my own knowledge on the various subjects discussed. This book will not only be an excellent resource for newcomers and experts in the G-quadruplex field, but also should be extremely informative for chemists, physicists and biologists interested in these fascinating G-quadruplex structures, the origins of which preceded the discovery of double helix by 50 years. -- Natalia Gromak, University of Oxford The Biochemist Evolution


"A very useful resource that is an up-to-date record of the state of the field...I am sure that this book will remain as a useful resource for many years. ChemBioChem, 2008, 9, 642-645 (Keith Fox) ""Quadruplex Nucleic Acids, edited by Stephen Neidle and Shankar Balasubramanian, contains the most up-to-date information in this rapidly growing field, written by worldclass experts. It is an impressive fusion of knowledge, in a format volume of 297 pages, conveniently split into ten chapters."" ""In summary, I believe Quadruplex Nucleic Acids provides a very comprehensive and up-to-date overview of chemical, physical and biological properties of G-quadruplex structures. The book not only covers these topics and concepts seamlessly, but also leaps into future directions, discussing potential applications of such structures in nanoscience and supramolecular chemistry. I thoroughly enjoyed reading this well-written and structured book and broadening my own knowledge on the various subjects discussed. This book will not only be an excellent resource for newcomers and experts in the G-quadruplex field, but also should be extremely informative for chemists, physicists and biologists interested in these fascinating G-quadruplex structures, the origins of which preceded the discovery of double helix by 50 years."" -- Natalia Gromak, University of Oxford The Biochemist Evolution"


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