Overview

Revised for paperback edition, with new appendices Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations. The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future. The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors.

Full Product Details

Author:   Peter McGuffin (Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Denmark Hill, London, UK) ,  Michael J Owen (Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK) ,  Irving I Gottesman (University of Minnesota, USA)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 16.80cm , Height: 2.70cm , Length: 24.10cm
Weight:   0.841kg
ISBN:  

9780198564867

ISBN 10:   0198564864
Pages:   496
Publication Date:   23 September 2004
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   To order  
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Table of Contents

Part 1: Basic Principles 1: Owen & O'Donovan: Basic molecular genetics 2: McGuffin & Cardno: Quantitative genetics 3: Sham & McGuffin: Linkage and association Part 2: The Genetics of Normal and Abnormal Development 4: Plomin, Happe & Caspi: Personality and cognitive abilities 5: Thapar & Clayton-Smith: Genetics of mental retardation 6: Williams: Reading and language disorders 7: Thapar: Childhood disorders Part 3: The Genetics of Abnormal Behaviour in Adult Life 8: McGuffin, Moffitt & Thapar: Personality disorders 9: Jones, Kent & Craddock: Genetics of affective disorders 10: Owen, O'Donovan & Gottesman: Schizophrenia 11: Ball & Collier: Substance misuse 12: Eley, Collier & McGuffin: Anxiety and eating disorders 13: Liddell, Williams & Owen: The dementias D - Applications and Implications 14: Kerwin & Arranz: Pharmacogenetics 15: Scourfield & Owen: Genetic counselling 16: Farmer: Ethical considerations 17: Owen, McGuffin & Gottesman: The future and post-genomic psychiatry

Reviews

`This admirable collection provides us with a comprehensive overview of the state-of-the-art of psychiatric genetics and is recommended reading for anyone active or interested in this field.' Genes, Brains and Behaviour

The advent of the genomic era and recent progress in the fields of statistics and computation methodology are neatly balanced with the traditional cornerstones of psychiatric genetics, such as twin and adoption studies, in this impressive text on psychiatric genetics and genomics. American Journal of Psychiatry Vol 162, No 11 From reviews of the hardback: It is timely to see such an excellent textbook... Aimed at graduate level students, this book is complex enough to be thorough, but clear with enough background to be accessible... the coverage is comprehensive and the flow logical... The text is uniformly well written and achieves a successful integration. The Lancet A good introduction and reference book for professionals interested in psychiatric genetics such as psychiatrists, clinical psychologists and neuroscientists... the book you want to have on your bookshelf to look up material and obtain a complete and balanced picture of the field. Psychological Medicine

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