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OverviewThis text is an introduction to the field of proteomics, an interdisciplinary science that includes biology, bioinformatics, and protein chemistry. The purpose of this book is to provide the active researcher with an overview of the types of questions being addressed in proteomics studies and the technologies used to address those questions. Key subjects covered in this book include: an assessment of the limitations of this approach and outlines new developments in mass spectrometry that will advance future research; high-throughput recombinant DNA cloning methods used to systematically clone all of the open reading frames of an organism into plasmid vectors for large scale protein expression and functional studies such as protein-protein interactions with the two-hybrid system; protein structure; an overview of large-scale experimental attempts to determine the three-dimensional structures of representative sets of proteins; and computational approaches to determining the three-dimensional structure of proteins. Proteomics provides a starting point for researchers who would like a theoretical understanding of the new technologies in the field, and obtain a solid grasp of the fundamentals before integrating new tools into their experiments. Written with attention to detail, but without being overwhelmingly technical, the book is a user-friendly guide that should prove useful to most biologists. Full Product DetailsAuthor: Timothy PalzkillPublisher: Springer Imprint: Springer Edition: 2002 ed. Dimensions: Width: 15.50cm , Height: 0.90cm , Length: 23.50cm Weight: 0.830kg ISBN: 9780792375654ISBN 10: 0792375653 Pages: 128 Publication Date: 30 November 2001 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: In Print  This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsProtein Identification and Analysis.- Protein Expression Mapping.- High-Throughput Cloning of Open Reading Frames.- Protein-Protein Interaction Mapping: Experimental.- Protein-Protein Interaction Mapping: Computational.- Protein Arrays and Protein Chips.- Conclusions.ReviewsAuthor InformationTimothy Palzkill is an Associate Professor in the Department of Molecular Virology & Microbiology and the Department of Biochemistry at the Baylor College of Medicine Tab Content 6Author Website:Countries AvailableAll regions |
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