Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance

Author:   Judith Blaine
Publisher:   Springer International Publishing AG
Edition:   1st ed. 2016
ISBN:  

9783319433578


Pages:   145
Publication Date:   28 October 2016
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance


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Overview

Recent work has begun to elucidate at the molecular level how albumin is handled by the kidney and how albuminuria develops in various proteinuric diseases including minimal change disease and focal segmental glomerulosclerosis. This volume provides a comprehensive overview of the renal handling of albumin – from basic mechanisms to the pathophysiology of proteinuric diseases. In describing the basic mechanisms of albuminuria, a particular highlight will be the focus on  advanced imaging techniques such as intravital microscopy that have allowed a detailed “window” into albumin transit through the kidney.   The volume will cover the epidemiological studies which show that albuminuria is a strong and independent marker of kidney disease progression and cardiovascular events, the molecular details of albumin handling in the kidney at the level of the glomerulus and the proximal tubule and the pathophysiology of proteinuric diseases including minimal change disease, membranousnephropathy, focal segmental glomerulosclerosis and diabetic nephropathy.

Full Product Details

Author:   Judith Blaine
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2016
Dimensions:   Width: 15.50cm , Height: 1.10cm , Length: 23.50cm
Weight:   3.613kg
ISBN:  

9783319433578


ISBN 10:   3319433571
Pages:   145
Publication Date:   28 October 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Evaluation and Epidemiology of Proteinuria.- 2. Glomerular Mechanisms of Proteinuria.- 3. Tubular Mechanisms of Proteinuria.- 4. Pathophysiology of Diabetic Nephropathy.- 5. Immune-Mediated Mechanisms of Proteinuria.- 6. Minimal Change Disease.- 7. Focal segmental glomerulosclerosis and its pathophysiology.

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